| Autor: |
Olivieri DJ; medical student at the Warren Alpert Medical School of Brown University, Providence, RI., Heffernan DS; trauma and critical care surgeon and an Associate Professor of Surgery at the Warren Alpert Medical School of Brown University, Providence, RI., Koness RJ; surgical oncologist and a Clinical Assistant Professor of Surgery at the Warren Alpert Medical School of Brown University, Providence, RI. He also is the Director of the Breast Health Program at Roger Williams Medical Center, Providence, RI. |
| Jazyk: |
angličtina |
| Zdroj: |
Rhode Island medical journal (2013) [R I Med J (2013)] 2021 Sep 01; Vol. 104 (7), pp. 42-45. Date of Electronic Publication: 2021 Sep 01. |
| Abstrakt: |
We report a 73-year-old male with recurrent amelanotic malignant melanoma of the left foot with in-transit metastases to the left thigh. In-transit metastatic melanoma can often represent a diagnostic and therapeutic challenge for physicians. This patient was treated with talimogene laherparepvec injections (T-VEC; Imlygic) in the left inguinal and the left plantar region every two weeks for one year as oncolytic viral therapy for advanced non- operable malignant melanoma. He then received consistent follow-up including blood work and PET scans every four months, and he also required further lymph node surgical dissection. To date, our patient has survived 3 years and 11 months, which is 27 months longer than the esti- mated median survival of 1 year 8 months for patients diagnosed with in-transit metastatic melanoma. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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