SARS-CoV-2 antibody seroprevalence among firefighters in Orange County, California.

Autor:	Vieira V; Department of Environmental and Occupational Health, University of California Irvine Susan and Henry Samueli College of Health Sciences, Irvine, California, USA vvieira@uci.edu.; University of California Irvine Center for Occupational and Environmental Health, Irvine, California, USA., Tang IW; Department of Environmental and Occupational Health, University of California Irvine Susan and Henry Samueli College of Health Sciences, Irvine, California, USA., Bartell S; Department of Environmental and Occupational Health, University of California Irvine Susan and Henry Samueli College of Health Sciences, Irvine, California, USA.; University of California Irvine Center for Occupational and Environmental Health, Irvine, California, USA., Zahn M; Orange County Health Care Agency, Santa Ana, California, USA., Fedoruk MJ; Department of Environmental and Occupational Health, University of California Irvine Susan and Henry Samueli College of Health Sciences, Irvine, California, USA.; University of California Irvine Center for Occupational and Environmental Health, Irvine, California, USA.
Jazyk:	angličtina
Zdroj:	Occupational and environmental medicine [Occup Environ Med] 2021 Nov; Vol. 78 (11), pp. 789-792. Date of Electronic Publication: 2021 Aug 25.
DOI:	10.1136/oemed-2021-107461
Abstrakt:	Objectives: We conducted serological SARS-CoV-2 antibody testing from October to November 2020 to estimate the SARS-CoV-2 seroprevalence among firefighters/paramedics in Orange County (OC), California. Methods: OC firefighters employed at the time of the surveillance activity were invited to participate in a voluntary survey that collected demographic, occupational and previous COVID-19 testing data, and a SARS-CoV-2 immunoglobulin (Ig)G antibody blood test. We collected venous blood samples using mobile phlebotomy teams that travelled to individual fire stations, in coordination with an annual tuberculosis testing campaign for firefighters employed by OC Fire Authority (OCFA), and independently for firefighters employed by cities. We estimated seroprevalence and assessed several potential predictors of seropositivity. Results: The seroprevalence was 5.3% among 923 OCFA personnel tested, with 92.2% participating. Among firefighters self-reporting a previous positive COVID-19 antibody or PCR test result, twenty-one (37%) did not have positive IgG tests in the current serosurvey. There were no statistically significant differences in demographic characteristics between cases and non-cases. Work city was a significant predictor of case status (p=0.015). Seroprevalence (4.8%) was similar when aggregated across seven city fire departments (42%-65% participation). In total, 1486°C fire personnel were tested. Conclusion: Using a strong serosurvey design and large firefighter cohort, we observed a SARS-CoV-2 IgG seroprevalence of 5.3%. The seroprevalence among OC firefighters in October 2020 was lower than the general county population estimated seroprevalence (11.5%) in August. The difference may be due in part to safety measures taken by OC fire departments at the start of the pandemic, as well as differences in antibody test methods and/or duration of antibody response. Competing Interests: Competing interests: None declared. (© Author(s) (or their employer(s)) 2021. No commercial re-use. See rights and permissions. Published by BMJ.)
Databáze:	MEDLINE
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