Technical characteristics and quality of grafts in liver procurement from brain-dead donors: A single-center study in Vietnamese population.
Autor: | Nguyen TK; Department of Gastrointestinal and Hepato-pancreato-biliary Surgery, Bach Mai Hospital, Hanoi, Viet Nam., Trinh HS; Department of Oncology, Viet Duc University Hospital, Hanoi, Viet Nam., Luong TH; Department of Surgery, Hanoi Medical University, Hanoi, Viet Nam., Ninh VK; Center of Organ Transplantation, Viet Duc University Hospital, Hanoi, Viet Nam., Pham GA; Department of Oncology, Viet Duc University Hospital, Hanoi, Viet Nam., Nguyen HH; Department of Gastrointestinal and Hepato-pancreato-biliary Surgery, Bach Mai Hospital, Hanoi, Viet Nam., Bui TN; Department of Oncology, Viet Duc University Hospital, Hanoi, Viet Nam., Dang KK; Department of Gastrointestinal and Hepato-pancreato-biliary Surgery, Bach Mai Hospital, Hanoi, Viet Nam., Hoang T; Center of Organ Transplantation, Viet Duc University Hospital, Hanoi, Viet Nam., Nguyen QN; Center of Organ Transplantation, Viet Duc University Hospital, Hanoi, Viet Nam. |
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Jazyk: | angličtina |
Zdroj: | Annals of medicine and surgery (2012) [Ann Med Surg (Lond)] 2021 Jul 31; Vol. 69, pp. 102654. Date of Electronic Publication: 2021 Jul 31 (Print Publication: 2021). |
DOI: | 10.1016/j.amsu.2021.102654 |
Abstrakt: | Introduction: Donor liver graft quality plays an especially important role that contributes to the success of organ transplantation. Almost all local and international authors are interested in the techniques and results of transplantation, however, in Vietnam, there have not been any studies that report the results of liver procurement from brain-dead donors from a technical perspective as well as the morphology and function of the transplanted organ. Materials and Method: This study is descriptive cross-section study with analysis of retrospective occurrences of a series of cases of liver procurement from brain-dead donors from March 2010 to March 2020. All cases were proceeded the multiple organ procurement with warm liver dissection and in vivo cannulation and perfusion. Results: The average age of brain-dead donors was 29.7 ± 10.7 (18-69), 92.16% of the harvested organs were of good quality macroscopically; and the rate of anatomical modification was 33.3% that occurred mostly in the left hepatic artery (LHA). Technically, warm dissection was proceeded in majority of cases (98,0%), the graft implantation was performed by this technique with mean cold ischemia time (CIT) of 190,0 ± 100,5 min and WIT of 74,0 ± 39,2 s. There were no complications relating to graft injuries occurring during procurement and no primary liver failure, good results accounted for 94.1% of the total number of transplants postoperatively. Conclusion: Multiple organ procurement with warm liver dissection and in vivo cannulation and perfusion was a safe technique and may be effective by avoiding any donor's damages in cold-phase dissection. Competing Interests: The authors declare that they have no conflicts of interests. (© 2021 The Authors.) |
Databáze: | MEDLINE |
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