Characteristics of 637 melanomas documented by 27 general practitioners on the Skin Cancer Audit Research Database.

Autor: Jimenez Balcells C; 4D Skin Cancer Clinic, Belmont North, NSW, Australia., Hay J; Upper Hutt Skin Clinic, Upper Hutt, Wellington, New Zealand., Keir J; Primary Care Clinical Unit, Faculty of Medicine, The University of Queensland, Herston, QLD, Australia., Rosendahl N; Faculty of Medicine, The University of Queensland, Herston, QLD, Australia., Coetzer-Botha M; Primary Care Clinical Unit, Faculty of Medicine, The University of Queensland, Herston, QLD, Australia., Wilson T; SCARD, Brisbane, QLD, Australia., Clark S; Faculty of Medicine, The University of Queensland, Herston, QLD, Australia.; Tehran University of Medical Sciences, Tehran, Iran.; Douglas Hanly Moir Pathology, Macquarie Park, NSW, Australia., Baade A; Gladstone GP Superclinic, Gladstone, QLD, Australia., Becker C; Wairarapa Skin Clinic, Masterton, New Zealand.; Wairarapa Hospital, Lansdowne, Masterton, New Zealand., Bookallil L; The University of New England, Armidale, NSW, Australia., Clifopoulos C; Primary Care Clinical Unit, Faculty of Medicine, The University of Queensland, Herston, QLD, Australia., Dicker T; Primary Care Clinical Unit, Faculty of Medicine, The University of Queensland, Herston, QLD, Australia., Denby MP; Silverdale Medical, Silverdale, Auckland, New Zealand., Duthie D; Darwin Skin Cancer Clinic, Parap, NT, Australia., Elliott C; Solarderm Skin Cancer Practice, Caboolture, QLD, Australia., Fishburn P; Primary Care Clinical Unit, Faculty of Medicine, The University of Queensland, Herston, QLD, Australia., Foley M; The Skin Clinic, Marlborough - Blenheim, New Zealand., Franck M; MoleSafe Skin Cancer Clinic, Windsor, VIC, Australia., Giam I; Skin2 Clinic, Deakin, ACT, Australia., Gordillo P; Cairns Skin Cancer Clinic, Cairns, QLD, Australia., Lilleyman A; Newcastle Skin Check, Charlestown, NSW, Australia., Macauley R; Bateau Bay Medical Centre, Bateau Bay, NSW, Australia., Maher J; Skin Cancer Ballarat, Alfredton, VIC, Australia., McPhee E; Emerald Medical Group, Emerald, QLD, Australia., Reid M; Nelson Bay Skin Cancer Clinic, Nelson Bay, NSW, Australia., Shirlaw B; Lakeside Medical, Springfield Lakes, QLD, Australia., Siggs G; Regency Medical Clinic, Sefton Park, SA, Australia., Spark R; Toukley Family Practice, Toukley, NSW, Australia., Stretch J; Bond University, Robina, QLD, Australia., van den Heever K; CQ Skin Cancer Clinic, Bucasia, QLD, Australia., van Rensburg T; Kippax Ochre Medical Centre, Holt, ACT, Australia., Watson C; Brisbane City Doctors, Brisbane, QLD, Australia., Kittler H; Vienna Dermatologic Imaging Research Group, Department of Dermatology, Medical University of Vienna, Vienna, Austria., Rosendahl C; Primary Care Clinical Unit, Faculty of Medicine, The University of Queensland, Herston, QLD, Australia.; Tehran University of Medical Sciences, Tehran, Iran.
Jazyk: angličtina
Zdroj: The Australasian journal of dermatology [Australas J Dermatol] 2021 Nov; Vol. 62 (4), pp. 496-503. Date of Electronic Publication: 2021 Aug 23.
DOI: 10.1111/ajd.13705
Abstrakt: Background and Objective: Most melanomas (including melanomas in situ), in Australasia, are treated by general practitioners (GPs). Previously undescribed, the characteristics of a series of melanomas treated by multiple GPs are examined.
Patients and Methods: Six hundred and thirty-seven melanomas treated by 27 Australasian GPs during 2013 and documented on the Skin Cancer Audit Research Database (SCARD) were analysed by anatomical site, subtype, Breslow thickness, diameter, associated naevi and linked adverse outcomes.
Results: Most melanomas (59.7%) were on males, mean age at diagnosis being 62.7 years (range 18-96). Most (65.0%) were in situ, with a high incidence of lentiginous melanoma (LM) (38.8%) and 32% were naevus associated. Most LM (86.4%) were in situ, compared to 55% of superficial spreading melanoma (SSM) (P < 0.0001). There was male predominance on the head, neck and trunk and female predominance on extremities. There was no significant association between Breslow thickness and diameter, with small melanomas as likely to be thick as large melanomas, and melanomas ≤3 mm diameter, on average, more likely to be invasive than larger melanomas. There was a positive correlation between age and both melanoma diameter and Breslow thickness. Seven cases progressed to melanoma-specific death: Five nodular melanoma (NM) and two SSM, one of which was thin (Breslow thickness 0.5 mm).
Conclusions: A large series of melanomas treated by Australasian GPs were predominantly in situ, with a high proportion of LM subtype. With implications for GP training, NM linked to death was over-represented and there was a novel finding that older patients had larger diameter melanomas.
(© 2021 The Australasian College of Dermatologists.)
Databáze: MEDLINE
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