Carcinosarcoma ex pleomorphic adenoma of the parotid gland: a case report.

Autor: Almubarak AA; Department of Surgery, College of Medicine, King Saud bin Abdulziz University for Health Sciences, Riyadh, Saudi Arabia., Alotaibi SK; Department of Surgery, College of Medicine, Shaqra University, Riyadh, Saudi Arabia., Alghamdi FR; Department of Otolaryngology, Head & Neck Surgery, Prince Sultan Military Medical City, Riyadh, Saudi Arabia., Alqahtani S; Department of Otolaryngology, Head & Neck Surgery, Prince Sultan Military Medical City, Riyadh, Saudi Arabia., Alahmadi RM; Department of Otolaryngology, Head & Neck Surgery, Prince Sultan Military Medical City, Riyadh, Saudi Arabia.
Jazyk: angličtina
Zdroj: Journal of surgical case reports [J Surg Case Rep] 2021 Aug 17; Vol. 2021 (8), pp. rjab361. Date of Electronic Publication: 2021 Aug 17 (Print Publication: 2021).
DOI: 10.1093/jscr/rjab361
Abstrakt: Carcinosarcoma ex pleomorphic adenoma is an extremely rare malignant neoplasm of the salivary gland that originates from a pre-existing benign tumor. Malignant transformation of the pleomorphic adenoma is extremely rare. The management of carcinosarcoma ex pleomorphic adenoma remains challenging because of its rarity, behavioral aggressiveness and resemblance to benign pleomorphic adenoma. Herein, we present the case of a 75-year-old male resident of Saudi Arabia with a history of a swelling in the right parotid gland for more than 25 years, which grew slowly with time. He underwent surgical removal with superficial parotidectomy. Afterward, histological examination of the resected tumor revealed features of carcinosarcoma, and he was diagnosed with carcinosarcoma ex pleomorphic adenoma. He presented again with recurrence of the tumor, which was managed with total parotidectomy and a combination of radiotherapy and chemotherapy. At 12-month follow-up, the patient showed no evidence of disease recurrence or distant metastasis.
(Published by Oxford University Press and JSCR Publishing Ltd. All rights reserved. © The Author(s) 2021.)
Databáze: MEDLINE
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