Evaluation of simulators for x-ray speckle-based phase contrast imaging.

Autor:	Quénot L; Inserm UA7 Strobe, Université Grenoble Alpes, Grenoble, France., Brun E; Inserm UA7 Strobe, Université Grenoble Alpes, Grenoble, France., Létang JM; Univ Lyon, INSA Lyon, Université Claude Bernard Lyon 1, UJM-Saint Étienne, CNRS, Inserm, CREATIS UMR 5220, U1206, F-69373, Lyon, France., Langer M; Univ Lyon, INSA Lyon, Université Claude Bernard Lyon 1, UJM-Saint Étienne, CNRS, Inserm, CREATIS UMR 5220, U1206, F-69373, Lyon, France.; Univ. Grenoble Alpes, CNRS, UMR 5525, VetAgro Sup, Grenoble INP, TIMC, 38000 Grenoble, France.
Jazyk:	angličtina
Zdroj:	Physics in medicine and biology [Phys Med Biol] 2021 Sep 03; Vol. 66 (17). Date of Electronic Publication: 2021 Sep 03.
DOI:	10.1088/1361-6560/ac1f38
Abstrakt:	X-ray phase contrast imaging (PCI) denotes a group of highly sensitive imaging techniques that permits imaging at scales ranging from nanoscopic to the medical. Recently introduced, speckle-based imaging has seen a rapid development because of its experimental simplicity and its capability to retrieve the refraction, the scattering and the absorption of a sample using a conventional x-ray set-up. Precise simulation would permit to optimise the imaging setups for different applications, but until now works on simulation of x-ray speckle-based PCI have been very few. In this work we evaluate different simulation codes, based on Monte-Carlo, analytical ray-tracing and wave-optics Fresnel propagation. The simulation results are compared to both synchrotron and conventional imaging experiments to permits their validation. We obtain a strong similarity between simulated and experimental data. We discuss the validity and applicability of each approach. (© 2021 Institute of Physics and Engineering in Medicine.)
Databáze:	MEDLINE
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