Effect of early awake prone positioning application on prognosis in patients with acute respiratory failure due to COVID-19 pneumonia: a retrospective observational study.

Autor: Altinay M; Istanbul Sisli Hamidiye Etfal Health Practice and Research Center, University of Health Sciences, Department of Anesthesiology and Reanimation, Istanbul, Turkey., Sayan I; Istanbul Sisli Hamidiye Etfal Health Practice and Research Center, University of Health Sciences, Department of Anesthesiology and Reanimation, Istanbul, Turkey., Turk HS; Istanbul Sisli Hamidiye Etfal Health Practice and Research Center, University of Health Sciences, Department of Anesthesiology and Reanimation, Istanbul, Turkey. Electronic address: hacersebnem@yahoo.com.tr., Cinar AS; Istanbul Sisli Hamidiye Etfal Health Practice and Research Center, University of Health Sciences, Department of Anesthesiology and Reanimation, Istanbul, Turkey., Sayın P; Istanbul Sisli Hamidiye Etfal Health Practice and Research Center, University of Health Sciences, Department of Anesthesiology and Reanimation, Istanbul, Turkey., Yucel T; Istanbul Sisli Hamidiye Etfal Health Practice and Research Center, University of Health Sciences, Department of Anesthesiology and Reanimation, Istanbul, Turkey., Islamoglu S; Istanbul Sisli Hamidiye Etfal Health Practice and Research Center, University of Health Sciences, Department of Anesthesiology and Reanimation, Istanbul, Turkey., Ozkan MT; Istanbul Sisli Hamidiye Etfal Health Practice and Research Center, University of Health Sciences, Department of Anesthesiology and Reanimation, Istanbul, Turkey., Cetiner I; Istanbul Sisli Hamidiye Etfal Health Practice and Research Center, University of Health Sciences, Department of Anesthesiology and Reanimation, Istanbul, Turkey.
Jazyk: angličtina
Zdroj: Brazilian journal of anesthesiology (Elsevier) [Braz J Anesthesiol] 2022 Mar-Apr; Vol. 72 (2), pp. 194-199. Date of Electronic Publication: 2021 Aug 16.
DOI: 10.1016/j.bjane.2021.07.029
Abstrakt: Background: We evaluated the effect of early awake prone position administration on oxygenation and intubation requirements and short-term mortality in patients with acute respiratory failure due to coronavirus disease 2019 (COVID-19) pneumonia.
Methods: This is an observational-cohort study. Patients receiving mask oxygen therapy in our intensive care units because of acute respiratory failure due to COVID-19 pneumonia were included. The Awake Prone Position (APP) group consisted of patients who were applied awake prone position, whereas non-APP group consisted of patients who were not applied awake prone position. PaCO 2 , PaO 2 , pH, SpO 2 values and PaO 2 /FiO 2 ratios were recorded at the beginning and 24th hour. Demographic data, comorbidities, intubation requirements, ventilator-free days, length of intensive care unit stay and short-term mortality of the patients were recorded.
Results: The data of total 225 patients were examined, and 48 patients who met our study criteria were included. At the 24th hour, the median SpO 2 value of the APP group was 95%, the median PaO 2 value was 82 mmHg, whereas the SpO 2 value of the non-APP group was 90% and the PaO 2 value was 66 mmHg. (p = 0.001, p = 0.002). There was no statistically significant difference between the groups in length of intensive care unit stay and ventilator-free days, but short-term mortality and intubation requirements was lower in the APP group (p = 0.020, p = 0.001) CONCLUSION: Awake prone position application in patients receiving non-rebreather mask oxygen therapy for respiratory failure due to COVID-19 pneumonia improves oxygenation and decreases the intubation requirements and mortality.
(Copyright © 2021 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. All rights reserved.)
Databáze: MEDLINE
Externí odkaz: