| Autor: |
Zhu BL; Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China., Wu YZ; Department of First Clinical Medical School, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China., Cai ZM; Department of First Clinical Medical School, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China., Liao CW; Department of First Clinical Medical School, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China., Sun LQ; Department of Neurology, Wenzhou Medical Univerisity Affiliated Yueqing Hospital, Wenzhou, Zhejiang, People's Republic of China., Liu ZP; Department of First Clinical Medical School, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China., Chen HM; Department of First Clinical Medical School, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China., Huang XR; Department of Neurology, Ruian People's Hospital, Wenzhou, Zhejiang, People's Republic of China., Feng RQ; Department of First Clinical Medical School, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China., Ye SL; Department of First Clinical Medical School, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China., Lin QL; Department of Neurology, Yongjia People's Hospital, Wenzhou, Zhejiang, People's Republic of China., Zhou XD; Department of Neurology, Pingyang People's Hospital, Wenzhou, Zhejiang, People's Republic of China., Wang L; Department of Public Health, Robbins College of Health and Human Sciences, Baylor University, Waco, TX, USA., Zhang MM; Department of Neurology, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, People's Republic of China., Yang B; School of Public Health and Management, Wenzhou Medical University, Wenzhou, Zhejiang, People's Republic of China. |
| Abstrakt: |
Nutritional Risk Screening index is a standard tool to assess nutritional risk, but epidemiological data are scarce on controlling nutritional status (CONUT) as a prognostic marker in acute haemorrhagic stroke (AHS). We aimed to explore whether the CONUT may predict a 3-month functional outcome in AHS. In total, 349 Chinese patients with incident AHS were consecutively recruited, and their malnutrition risks were determined using a high CONUT score of ≥ 2. The cohort patients were divided into high-CONUT (≥ 2) and low-CONUT (< 2) groups, and primary outcomes were a poor functional prognosis defined as the modified Rankin Scale (mRS) score of ≥ 3 at post-discharge for 3 months. Odds ratios (OR) with 95 % confidence intervals (CI) for the poor functional prognosis at post-discharge were estimated by using a logistic analysis with additional adjustments for unbalanced variables between the high-CONUT and low-CONUT groups. A total of 328 patients (60·38 ± 12·83 years; 66·77 % male) completed the mRS assessment at post-discharge for 3 months, with 172 patients at malnutrition risk at admission and 104 patients with a poor prognosis. The levels of total cholesterol and total lymphocyte counts were significantly lower in high-CONUT patients than low-CONUT patients ( P = 0·012 and < 0·001, respectively). At 3-month post discharge, there was a greater risk for the poor outcome in the high-CONUT compared with the low-CONUT patients at admission (OR: 2·32, 95 % CI: 1·28, 4·17). High-CONUT scores independently predict a 3-month poor prognosis in AHS, which helps to identify those who need additional nutritional managements. |
