Renal graft malakoplakia masquerading post-transplant lymphoproliferative disorder.

Autor: Patel MR; Department of Nephrology, SGPGIMS, Lucknow, Uttar Pradesh, India., Thammishetti V; Department of Nephrology, SGPGIMS, Lucknow, Uttar Pradesh, India., Agarwal S; Department of Radiology, SGPGIMS, Lucknow, Uttar Pradesh, India., Lal H; Radiodiagnosis, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, India hiralal2007@yahoo.co.in.
Jazyk: angličtina
Zdroj: BMJ case reports [BMJ Case Rep] 2021 Aug 16; Vol. 14 (8). Date of Electronic Publication: 2021 Aug 16.
DOI: 10.1136/bcr-2021-244228
Abstrakt: A 45-year-old woman presented to us in March 2019 with complaints of fever and right lower quadrant abdominal pain for 1 month. She had undergone renal transplantation in 2017 for end-stage renal disease and developed four episodes of urinary tract infection in the next 16 months post transplantation, which were treated based on culture reports. She was subsequently kept on long-term prophylaxis with trimethoprim and sulfamethoxazole. Her present laboratory parameters showed a normal blood picture and elevated creatinine. Urine culture grew Escherichia coli Non-contrast CT of the abdomen-pelvis revealed an endo-exophytic hyperdense mass in the graft kidney showing local infiltration and associated few regional lymph nodes. PET-CT revealed the soft-tissue mass and regional lymph nodes to be hypermetabolic, raising the possibility of lymphoma. However, biopsy showed features of malakoplakia. She was subsequently initiated on long-term antibiotic therapy and her immunosuppression decreased.
Competing Interests: Competing interests: None declared.
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Databáze: MEDLINE