Network organization of the plant immune system: from pathogen perception to robust defense induction.

Autor: Delplace F; Laboratoire des Interactions Plantes-Microbes-Environnement, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, INRAE, CNRS, Université de Toulouse, Castanet-Tolosan, 31326, France., Huard-Chauveau C; Laboratoire des Interactions Plantes-Microbes-Environnement, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, INRAE, CNRS, Université de Toulouse, Castanet-Tolosan, 31326, France., Berthomé R; Laboratoire des Interactions Plantes-Microbes-Environnement, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, INRAE, CNRS, Université de Toulouse, Castanet-Tolosan, 31326, France., Roby D; Laboratoire des Interactions Plantes-Microbes-Environnement, Institut National de Recherche pour l'Agriculture, l'Alimentation et l'Environnement, INRAE, CNRS, Université de Toulouse, Castanet-Tolosan, 31326, France.
Jazyk: angličtina
Zdroj: The Plant journal : for cell and molecular biology [Plant J] 2022 Jan; Vol. 109 (2), pp. 447-470. Date of Electronic Publication: 2021 Sep 02.
DOI: 10.1111/tpj.15462
Abstrakt: The plant immune system has been explored essentially through the study of qualitative resistance, a simple form of immunity, and from a reductionist point of view. The recent identification of genes conferring quantitative disease resistance revealed a large array of functions, suggesting more complex mechanisms. In addition, thanks to the advent of high-throughput analyses and system approaches, our view of the immune system has become more integrative, revealing that plant immunity should rather be seen as a distributed and highly connected molecular network including diverse functions to optimize expression of plant defenses to pathogens. Here, we review the recent progress made to understand the network complexity of regulatory pathways leading to plant immunity, from pathogen perception, through signaling pathways and finally to immune responses. We also analyze the topological organization of these networks and their emergent properties, crucial to predict novel immune functions and test them experimentally. Finally, we report how these networks might be regulated by environmental clues. Although system approaches remain extremely scarce in this area of research, a growing body of evidence indicates that the plant response to combined biotic and abiotic stresses cannot be inferred from responses to individual stresses. A view of possible research avenues in this nascent biology domain is finally proposed.
(© 2021 Society for Experimental Biology and John Wiley & Sons Ltd.)
Databáze: MEDLINE
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