[Cancers of the pancreas at the National Hospital and University Center of Cotonou: epidemiological, diagnostic, therapeutic and prognostic features].

Autor:	Kpossou AR; Clinique Universitaire d´Hépato-gastroentérologie, Centre National Hospitalier Universitaire-Hubert Koutoukou Maga (CNHU-HKM), Cotonou, Bénin., Gbessi DG; Clinique Universitaire de Chirurgie Viscérale, Centre National Hospitalier Universitaire-Hubert Koutoukou Maga (CNHU-HKM), Cotonou, Bénin., Gnangnon FHR; Clinique Universitaire de Chirurgie Viscérale, Centre National Hospitalier Universitaire-Hubert Koutoukou Maga (CNHU-HKM), Cotonou, Bénin., Ba Boukari MM; Clinique Universitaire d´Hépato-gastroentérologie, Centre National Hospitalier Universitaire-Hubert Koutoukou Maga (CNHU-HKM), Cotonou, Bénin., Vignon RK; Clinique Universitaire d´Hépato-gastroentérologie, Centre National Hospitalier Universitaire-Hubert Koutoukou Maga (CNHU-HKM), Cotonou, Bénin., Sokpon CNDM; Clinique Universitaire d´Hépato-gastroentérologie, Centre National Hospitalier Universitaire-Hubert Koutoukou Maga (CNHU-HKM), Cotonou, Bénin., Sehonou J; Clinique Universitaire d´Hépato-gastroentérologie, Centre National Hospitalier Universitaire-Hubert Koutoukou Maga (CNHU-HKM), Cotonou, Bénin.
Jazyk:	francouzština
Zdroj:	The Pan African medical journal [Pan Afr Med J] 2021 May 06; Vol. 39, pp. 18. Date of Electronic Publication: 2021 May 06 (Print Publication: 2021).
DOI:	10.11604/pamj.2021.39.18.26261
Abstrakt:	Introduction: cancer is a major cause of death in the world. The purpose of this study is to evaluate the epidemiological, clinical, therapeutic and prognostic features of cancers of the pancreas (CP) at the National Hospital and University Center of Cotonou. Methods: we conducted a cross-sectional descriptive and analytical study with a prospective and retrospective data collection over a period of ten years, from 1 October 2009 to 31 October 2019. Results: out of 15.102 hospitalizations, we identified 72 cases of CP, reflecting a hospitalization rate of 0.5%. The average age of patients was 59 years. The sex-ratio (H/F) was 1.5. The main reason for consultation was abdominal pain. More than half (51.4%) of patients had metastatic tumor at the time of diagnosis. Histological evidence of adenocarcinoma was only reported in 15.1% of cases. The rate of operable patients was 37.5% while the rate of resectable patients was 2.7%. Palliative chemotherapy was given to 13.9% of patients. The average cost of treatment was 955.882,4 FCFA (23.9 times the Guaranteed Interprofessional Minimum Wage in Benin). Median overall survival was 6 months. Mortality rate was 86.9% (53/61), survival rate at one year was 31.4%, and zero at five years. Palliative surgery (p = 0.021) and chemotherapy (p = 0.023) improved patient survival. Conclusion: cancer of the pancreas, due to its non-specific signs and insidious outcome, is often diagnosed at a late stage. A metastatic tumor and the limited individual and institutional therapeutic possibilities lead to more pejorative prognosis. Competing Interests: Les auteurs ne déclarent aucun conflit d'intérêts. (Copyright: Aboudou Raïmi Kpossou et al.)
Databáze:	MEDLINE
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