Patch testing with ammonium persulfate: The North American Contact Dermatitis Group Experience, 2015-2018.

Autor: Warshaw EM; Department of Dermatology, Park Nicollet Health Services, Minneapolis, Minnesota; Department of Dermatology, University of Minnesota, Minneapolis, Minnesota; Department of Dermatology, Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota., Ruggiero JL; Department of Dermatology, Park Nicollet Health Services, Minneapolis, Minnesota; Department of Dermatology, Minneapolis Veterans Affairs Medical Center, Minneapolis, Minnesota; University of Minnesota Medical School, Minneapolis, Minnesota. Electronic address: Ruggi020@umn.edu., DeKoven JG; Division of Dermatology, Sunnybrook Health Sciences Centre, University of Toronto, Toronto, Ontario, Canada., Pratt MD; Division of Dermatology, University of Ottawa, Ottawa, Ontario, Canada., Silverberg JI; Department of Dermatology, The George Washington University School of Medicine and Health Sciences, Washington, DC., Maibach HI; Department of Dermatology, University of California San Francisco, San Francisco, California., Zug KA; Department of Dermatology, Dartmouth-Hitchcock Medical Center, Lebanon, New Hampshire., Atwater AR; Department of Dermatology, Duke University Medical Center, Durham, North Carolina., Taylor JS; Department of Dermatology, Cleveland Clinic, Cleveland, Ohio., Reeder MJ; Department of Dermatology, University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin., Sasseville D; Division of Dermatology, Montreal General Hospital, McGill University, Montreal, Quebec, Canada., Fowler JF Jr; Division of Dermatology, University of Louisville, Louisville, Kentucky., Fransway AF; Associates in Dermatology, Fort Myers, Florida., Belsito DV; Department of Dermatology, Columbia University Irving Medical School, New York, New York., DeLeo VA; Department of Dermatology, Keck School of Medicine, Los Angeles, California., Houle MC; Division of Dermatology, Centre Hospitalier Universitairede Quebec, Laval University, Quebec City, Quebec, Canada., Dunnick CA; Department of Dermatology, University of Colorado, Boulder, Colorado.
Jazyk: angličtina
Zdroj: Journal of the American Academy of Dermatology [J Am Acad Dermatol] 2022 Nov; Vol. 87 (5), pp. 1014-1023. Date of Electronic Publication: 2021 Aug 11.
DOI: 10.1016/j.jaad.2021.08.005
Abstrakt: Background: Ammonium persulfate (APS), an oxidizing agent used in hair products, manufacturing, and pool/spa water, can cause skin reactions, including allergic contact dermatitis.
Objective: To characterize positive patch test reactions to APS (2.5% petrolatum).
Methods: Retrospective analysis of patients tested to the North American Contact Dermatitis Group screening series from 2015 to 2018.
Results: Of 10,526 patients, 193 (1.8%) had positive patch test reactions to APS. Compared with APS-negative patients, APS-positive patients were significantly more likely to be male (43.2% vs 28.0%; P < .0001); have primary hand dermatitis (30.2% vs 22.0%; P = .0064), scattered generalized dermatitis (25.5% vs 17.9%; P = .0064), or trunk dermatitis (8.9% vs 4.9%; P = .0123); and have dermatitis that is occupationally related (22.2% vs 10.9%; P < .0001). More than half of the APS-positive reactions were currently relevant (57.0%); 19 (9.8%) were related to occupation, especially hairdressers (68.4%). Swimming pools/spas (23.3%) and hair care products (19.2%) were the most common sources of APS.
Limitations: Immediate reactions and follow-up testing were not captured.
Conclusion: The proportion of patients positive to APS was 1.8%. APS positivity was significantly associated with male sex and hand dermatitis. Swimming pool/spa chemicals were important sources of APS exposure.
Competing Interests: Conflicts of interest Dr Atwater received a Pfizer Independent Grant for Learning & Change and has consulted for Henkel. Dr Warshaw has received research funding from Wen by Chaz Dean and served as a consultant for Noven Pharmaceuticals and Wen by Chaz Dean. Dr Taylor owns shares of stock in Astra Zeneca, Cigna, Merck, Johnson & Johnson, and Opko Health; has consulted for Kao Brands and Monsanto (Bayer); is a member of the Cosmetic Ingredient Review Steering Committee; and has a nondependent child employed by Pfizer. Dr Sasseville receives royalties from UpToDate (Wolters Kluwer Health). Drs DeKoven, Pratt, Silverberg, Maibach, Zug, Reeder, Fowler, Fransway, Belsito, DeLeo, Houle, and Dunnick and Ms Ruggiero have no conflicts of interest to declare.
(Copyright © 2021 American Academy of Dermatology, Inc. Published by Elsevier Inc. All rights reserved.)
Databáze: MEDLINE
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