Discrepancies between clinical diagnosis and hospital autopsy: A comparative retrospective analysis of 1,112 cases.

Autor: Kurz SD; German Heart Institute Berlin, Institute for Anaesthesiology, Berlin, Germany.; Institute of Physiology, Berlin Institute of Health, Charite-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.; Department of Cardiovascular Surgery, Berlin Institute of Health, Charite-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany., Sido V; Department of Cardiovascular Surgery, Berlin Institute of Health, Charite-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany., Herbst H; Department of Pathology, Vivantes Klinikum Neukölln, Berlin, Germany., Ulm B; Independent statistical advice, Munich, Germany., Salkic E; German Heart Institute Berlin, Institute for Anaesthesiology, Berlin, Germany.; Department of Cardiology, Berlin Institute of Health, Charite-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany., Ruschinski TM; German Heart Institute Berlin, Institute for Anaesthesiology, Berlin, Germany., Buschmann CT; Institute of Legal Medicine, University Hospital Schleswig-Holstein Kiel/Lübeck, Lubeck, Germany., Tsokos M; Institute of Legal Medicine and Forensic Sciences, Berlin Institute of Health, Charite-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin, Humboldt-Universität zu Berlin, Berlin, Germany.
Jazyk: angličtina
Zdroj: PloS one [PLoS One] 2021 Aug 13; Vol. 16 (8), pp. e0255490. Date of Electronic Publication: 2021 Aug 13 (Print Publication: 2021).
DOI: 10.1371/journal.pone.0255490
Abstrakt: Aims: The aim of this study was to compare discrepancies between diagnosed and autopsied causes of death in 1,112 hospital autopsies and to determine the factors causing this discrepancies.
Methods: 1,112 hospital autopsies between 2010 and 2013 were retrospectively studied. Ante-mortem diagnoses were compared to causes of death as determined by autopsy. Clinical diagnoses were extracted from the autopsy request form, and post-mortem diagnoses were assessed from respective autopsy reports. Variables, such as sex, age, Body Mass Index, category of disease, duration of hospital stay and new-borns were studied in comparison to discrepancy. P-values were derived from the Mann-Whitney U test for the constant features and chi-2 test, p-values < 0,05 were considered significant.
Results: 73.9% (n = 822) patients showed no discrepancy between autopsy and clinical diagnosis. The duration of hospitalisation (6 vs. 9 days) and diseases of the cardiovascular system (61.7%) had a significant impact on discrepancies.
Conclusion: Age, cardiovascular diseases and duration of hospital stay significantly affect discrepancies in ante- and post-mortem diagnoses.
Competing Interests: The authors have declared that no competing interests exist.
Databáze: MEDLINE
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