Neutrophil-to-lymphocyte ratio and C-reactive protein in non-fatal suicidal attempts: A cross-sectional pilot study in Bangladesh.

Autor: Arafat SMY; Department of Psychiatry Enam Medical College and Hospital Dhaka Bangladesh., Karim AKMB; Department of Neurosurgery Enam Medical College and Hospital Dhaka Bangladesh., Hossain MF; Department of Psychiatry Enam Medical College and Hospital Dhaka Bangladesh., Menon V; Department of Psychiatry Jawaharlal Institute of Postgraduate Medical Education and Research (JIPMER) Puducherry India., Shoib S; Department of Psychiatry Jawaharlal Nehru Memorial Hospital (JLNMH) Srinagar Jammu and Kashmir India.
Jazyk: angličtina
Zdroj: Health science reports [Health Sci Rep] 2021 Aug 05; Vol. 4 (3), pp. e347. Date of Electronic Publication: 2021 Aug 05 (Print Publication: 2021).
DOI: 10.1002/hsr2.347
Abstrakt: Background: Precise identification of risk factors for suicide has been found as fundamentally challenging for the stakeholders. In search of that, the determination of potential biological markers of suicide has been scrutinizing in recent days. However, replicative studies across the culture and time are warranted to utilize the biomarkers in decision-making while considering suicide prevention.
Objectives: We aimed to measure the neutrophil-to-lymphocyte ratio (NLR) and C-reactive protein (CRP) in non-fatal suicidal attempts.
Methods: This cross-sectional study was conducted from August 2020 to May 2021. Data were collected from 26 hospitalized patients after an immediate non-fatal suicidal attempt. We collected blood samples and assessed the complete blood count, NLR, and CRP. Data were analyzed by Statistical Package for the Social Science version 24.0 and Microsoft Excel software. We performed the independent Mann-Whitney U test to determine the variations between the groups. A value <.05 was considered as the level of significance.
Results: The mean age of the study population was 24.1 (±7.3), more than half of them (n = 19, 73.1%) were female. The mode of attempt was either hanging (n = 13, 50.0%) or poisoning (n = 13, 50.0%). The previous attempt was noted in 12 (46.2%) cases. The mean CRP level was 16.8 (±30.2) mg/L and the mean NLR level was 8.3 (±6.8) for the total sample. Both the CRP and NLR were significantly higher among those who attempted hanging ( P  = .019 and .001).
Conclusions: The current study revealed preliminary findings on CRP and NLR among non-fatal suicides in Bangladesh where both of the parameters were significantly higher in non-fatal hanging.
Competing Interests: The authors declare there is no conflict of interest.
(© 2021 The Authors. Health Science Reports published by Wiley Periodicals LLC.)
Databáze: MEDLINE
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