Low-carb Diet in Hospitalized Late Pubertal Type 1 Diabetic Girls: A Short-Term CGM Study.

Autor: Öz NA; Department of Pediatrics, Faculty of Medicine, Duzce University, Konuralp, Duzce, Turkey.; Department of Pediatric Neurology, Ankara City Hospital, Ankara, Turkey., Arslanoglu I; Department of Pediatric Endocrinology, Duzce University, Konuralp, Duzce, Turkey., Cangür S; Department of Biostatistics, Faculty of Medicine, Duzce University, Konuralp, Duzce, Turkey., Bolu S; Department of Pediatric Endocrinology, Duzce University, Konuralp, Duzce, Turkey.; Department of Pediatrics, Faculty of Medicine, Adiyaman University, Adiyaman, Turkey., Kocabay K; Department of Pediatrics, Faculty of Medicine, Duzce University, Konuralp, Duzce, Turkey.
Jazyk: angličtina
Zdroj: Indian journal of endocrinology and metabolism [Indian J Endocrinol Metab] 2021 Jan-Feb; Vol. 25 (1), pp. 31-37. Date of Electronic Publication: 2021 Jul 21.
DOI: 10.4103/ijem.ijem_176_21
Abstrakt: Objective: We conducted the present study to observe potential short-term benefits or risks of low-carb diet (LCD).
Methods: This is a prospective randomized cross-over study. Type 1 diabetic girls were hospitalized in ternary groups for 7 days and each group randomly started with LCD or regular diet. Continuous glucose monitoring (CGM) was performed between 0 and 168 h.
Results: Twenty-eight subjects completed the study. Total energy, protein, and fat consumption were high ( P < 0.001); carbohydrate consumption and rapidly acting insulin dose were low ( P < 0.001 and P = 0.002, respectively) during LCD. Morning postprandial, noon postprandial, and evening preprandial capillary blood sugar levels were lower during LCD ( P = 0.013, 0.018, and 0.048, respectively).
Conclusion: LCD may have the advantage of better glycemic control despite lower insulin dose which is a favorable outcome with regard to weight control and atherosclerosis prevention. No adverse events were observed.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2021 Indian Journal of Endocrinology and Metabolism.)
Databáze: MEDLINE
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