Laboratory capacity assessments in 25 African countries at high risk of yellow fever, August-December 2018.

Autor: Johnson BW; Scientific Laboratory Consulting, Laporte, Colorado, United States of America., Demanou M; World Health Organization African Region Yellow Fever Laboratory, Ouagadougou, Burkina Faso.; Centre Pasteur Cameroon, Yaoundé, Cameroon., Fall G; Institut Pasteur Dakar, Dakar, Senegal., Betoulle JL; Scientific Laboratory, Atlanta, Georgia, United States of America., Obiekea C; National Reference Laboratory, Nigeria Centre for Disease Control, Abuja, Nigeria., Basile AJ; Centers for Disease Control and Prevention, Division of Vector-borne Diseases, Fort Collins, Colorado, United States of America., Domingo C; Robert Koch Institute, Berlin, Germany., Goodman C; Centers for Disease Control and Prevention, Division of Vector-borne Diseases, Fort Collins, Colorado, United States of America., Mossel E; Centers for Disease Control and Prevention, Division of Vector-borne Diseases, Fort Collins, Colorado, United States of America., Reusken C; Centre for Infectious Disease Control, National Institute for Public Health and the Environment, Bilthoven, The Netherlands., Staples E; Centers for Disease Control and Prevention, Division of Vector-borne Diseases, Fort Collins, Colorado, United States of America., de Morais JFM; Instituto Nacional de Investigacao em Saude, Luanda, Angola., Neto Z; Instituto Nacional de Investigacao em Saude, Luanda, Angola., Paixão P; Instituto Nacional de Investigacao em Saude, Luanda, Angola., Denon YE; National Public Health Laboratory, Cotonou, Benin., Glitho M; National Public Health Laboratory, Cotonou, Benin., Mahinou J; National Public Health Laboratory, Cotonou, Benin., Kagone T; Scientific Laboratory Consulting, Laporte, Colorado, United States of America.; World Health Organization African Region Yellow Fever Laboratory, Ouagadougou, Burkina Faso., Nakoune E; Institute Pasteur, Bangui, Central African Republic., Gamougam K; Hôpital General De Reference Nationale, N'Djamena, Chad., Simbu EP; National Institute for Biomedical Research, Kinshasha, Democratic Republic of Congo., Ahuka S; National Institute for Biomedical Research, Kinshasha, Democratic Republic of Congo., Mombouli JV; Institut National de Santé Publique, Brazzaville, Republic of Congo., Goma-Nkoua C; Institut National de Santé Publique, Brazzaville, Republic of Congo., Adjogoua EV; Institut Pasteur de Côte d'Ivoire, Abidjan, Côte d'Ivoire., Tayachew A; Ethiopian Public Health Institute, Virology and Rickettsiology Unit, Addis Ababa, Ethiopia., Beyene B; World Health Organization Laboratory, Ethiopia., Sanneh B; National Health Laboratory Services, Royal Victoria Teaching Hospital, Banjul, The Gambia., Jarju ML; National Health Laboratory Services, Royal Victoria Teaching Hospital, Banjul, The Gambia., Mendy A; National Health Laboratory Services, Royal Victoria Teaching Hospital, Banjul, The Gambia., Amelor DK; National Public Health and Reference Laboratory, Public Health Division, Ghana Health Service, Korle-Bu, Accra, Ghana., Ofosu-Appiah L; National Public Health and Reference Laboratory, Public Health Division, Ghana Health Service, Korle-Bu, Accra, Ghana., Opare D; National Public Health and Reference Laboratory, Public Health Division, Ghana Health Service, Korle-Bu, Accra, Ghana., Antwi L; National Public Health and Reference Laboratory, Public Health Division, Ghana Health Service, Korle-Bu, Accra, Ghana., Adade R; National Public Health and Reference Laboratory, Public Health Division, Ghana Health Service, Korle-Bu, Accra, Ghana., Magassouba N; Laboratoire de Reference des Fièvres Hémorragiques, Conakry, Guinée., Gomes SF; Laboratoire National de Sante Publique, Bissau, Guinea-Bissau., Limbaso S; Center for Virus Research, Kenya Medical Research Institute, Nairobi, Kenya., Lutomiah J; Center for Virus Research, Kenya Medical Research Institute, Nairobi, Kenya., Gbelee B Jr; National Public Health Reference Laboratory, National Public Health Institute of Liberia, Charlesville, Liberia., Dogba J; National Public Health Reference Laboratory, National Public Health Institute of Liberia, Charlesville, Liberia., Cisse I; Institut National de Santé Publique Laboratoire de Fièvre Jaune, Bamako, Mali., Idde Z; Niamey National Hospital, Niamey, Niger., Ihekweazu C; National Reference Laboratory, Nigeria Centre for Disease Control, Abuja, Nigeria., Mba N; National Reference Laboratory, Nigeria Centre for Disease Control, Abuja, Nigeria., Faye O; Institut Pasteur Dakar, Dakar, Senegal., Faye O; Institut Pasteur Dakar, Dakar, Senegal., Sall AA; Institut Pasteur Dakar, Dakar, Senegal., Koroma Z; National Public Health Laboratory, Lakka, Sierra Leone., Juma MA; National Public Health Laboratory, Juba, South Sudan., Maror JA; National Public Health Laboratory, Juba, South Sudan., Eldigail M; Public Health Laboratory, Khartoum, Sudan., Elduma AH; Public Health Laboratory, Khartoum, Sudan., Elageb R; Public Health Laboratory, Khartoum, Sudan., Badziklou K; Laboratoire de Sérologie, Institut National d'Hygiène, Lomé, Togo., Komla KA; Laboratoire de Sérologie, Institut National d'Hygiène, Lomé, Togo., Kayiwa J; Uganda Virus Research Institute, Entebbe, Uganda., Lutwama JJ; Uganda Virus Research Institute, Entebbe, Uganda., Hampton L; Gavi Secretariat, Geneva, Switzerland., Mulders MN; Department of Immunizations, Vaccines and Biologicals, World Health Organization, Geneva, Switzerland.
Jazyk: angličtina
Zdroj: The Pan African medical journal [Pan Afr Med J] 2021 Apr 27; Vol. 38, pp. 402. Date of Electronic Publication: 2021 Apr 27 (Print Publication: 2021).
DOI: 10.11604/pamj.2021.38.402.28886
Abstrakt: Introduction: accurate and timely laboratory diagnosis of yellow fever (YF) is critical to the Eliminate Yellow Fever Epidemics (EYE) strategy. Gavi, the Vaccine Alliance recognized the need to support and build capacity in the national and regional laboratories in the Global YF Laboratory Network (GYFLN) as part of this strategy.
Methods: to better understand current capacity, gaps and needs of the GYFLN laboratories in Africa, assessments were carried out in national and regional reference laboratories in the 25 African countries at high risk for YF outbreaks that were eligible for new financial support from Gavi.
Results: the assessments found that the GYFLN in Africa has high capacity but 21% of specimens were not tested due to lack of testing kits or reagents and approximately 50% of presumptive YF cases were not confirmed at the regional reference laboratory due to problems with shipping.
Conclusion: the laboratory assessments helped to document the baseline capacities of these laboratories prior to Gavi funding to support strengthening YF laboratories.
Competing Interests: The authors declare no competing interests.
(Copyright: Barbara Wilmot Johnson et al.)
Databáze: MEDLINE