Acute necrotizing eosinophilic myocarditis possibly triggered by an antimigraine drug as an uncommon cause of acute heart failure: a case report.

Autor:	Beck-da-Silva L; Cardiology Division, Hospital Moinhos de Vento, Rua Ramiro Barcelos, 910, CEP: 90035-003, Porto Alegre, RS, Brazil.; Graduate Program in Cardiovascular Sciences, Universidade Federal do Rio Grande do Sul (UFRGS), Porto Alegre, Brazil., Maulaz A; Neurology Division, Hospital Moinhos de Vento, Porto Alegre, Brazil., Schvartzman P; Radiology Division, Hospital Moinhos de Vento, Porto Alegre, Brazil., Oliveira FH; Pathology Division, Hospital Moinhos de Vento, Porto Alegre, Brazil., Stifft J; Gastroenterology Division, Hospital Moinhos de Vento, Porto Alegre, Brazil., Astigarraga C; Hematology Division, Hospital Moinhos de Vento, Porto Alegre, Brazil., Kronfeld M; Internal Medicine Division, Hospital Moinhos de Vento, Porto Alegre, Brazil.
Jazyk:	angličtina
Zdroj:	European heart journal. Case reports [Eur Heart J Case Rep] 2021 Aug 09; Vol. 5 (8), pp. ytab286. Date of Electronic Publication: 2021 Aug 09 (Print Publication: 2021).
DOI:	10.1093/ehjcr/ytab286
Abstrakt:	Background: Epigastric or chest pain with an abnormal electrocardiogram (ECG) in a young, otherwise healthy patient should trigger an investigation to rule out myocarditis. The myocarditis covers a wide spectrum of severity. The search for the aetiologic factor could be definitive for the success of therapy. Case Summary: A previously healthy 29-year-old woman presented to the Emergency Room with epigastric pain, eosinophilia, and an abnormal ECG. A thorough evaluation including cardiac magnetic resonance and endomyocardial biopsy was undertaken. A diagnosis of acute necrotizing eosinophilic myocarditis was made. Discussion: The case is particularly unique for its suspected predisposing trigger: an antimigraine drug. A possible systemic hypersensitivity reaction, reflected by the occurrence of concomitant severe serum eosinophilia, acute myocarditis, and central nervous system vasculitis, was successfully treated with steroids, further supporting the diagnosis. (© The Author(s) 2021. Published by Oxford University Press on behalf of the European Society of Cardiology.)
Databáze:	MEDLINE
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