Secondary Immune Thrombocytopenia (ITP) Associated with ChAdOx1 Covid-19 Vaccination - A Case Report.

Autor:	Koch M; Department of Medicine, Hematology Division, University Hospital Carl Gustav Carus, Dresden, Germany., Fuld S; Department of Medicine, Nephrology Division, University Hospital Carl Gustav Carus, Dresden, Germany., Middeke JM; Department of Medicine, Hematology Division, University Hospital Carl Gustav Carus, Dresden, Germany., Fantana J; Department of Medicine, Emergency and Intensive Medicine Division, University Hospital Carl Gustav Carus, Dresden, Germany., von Bonin S; Department of Medicine, Emergency and Intensive Medicine Division, University Hospital Carl Gustav Carus, Dresden, Germany., Beyer-Westendorf J; Department of Medicine, Hematology Division, University Hospital Carl Gustav Carus, Dresden, Germany.
Jazyk:	angličtina
Zdroj:	TH open : companion journal to thrombosis and haemostasis [TH Open] 2021 Jul 30; Vol. 5 (3), pp. e315-e318. Date of Electronic Publication: 2021 Jul 30 (Print Publication: 2021).
DOI:	10.1055/s-0041-1731774
Abstrakt:	Novel mRNA and vector-based covid-19 vaccinations have shown high efficacy in preventing symptomatic COVID-19 infections. Compared with the number of performed vaccinations, rates of severe side effects seem low. Rare prothrombotic coagulation disorders with suspected association to ChAdOx1 nCoV-19 (AstraZeneca) have been reported. These cases have gathered considerable media attention and caused a temporary pause of usage of the AstraZeneca vaccine in Europe and several other countries and are currently discussed as vaccine-induced immune thrombotic thrombocytopenia (VITT). However, hemorrhagic complications from ChAdOx1 nCoV-19 vaccination have also been reported but, so far, received less public attention despite considerable potential for life-threatening complications. Here we present a case of severe immune thrombocytopenia after ChAdOx1 covid-19 vaccination and its successful primary management. Competing Interests: Conflict-of-Interest Disclosure The authors declare no competing financial interests. (The Author(s). This is an open access article published by Thieme under the terms of the Creative Commons Attribution License, permitting unrestricted use, distribution, and reproduction so long as the original work is properly cited. ( https://creativecommons.org/licenses/by/4.0/ ).)
Databáze:	MEDLINE
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