Dysglycemia and Abnormal Adiposity Drivers of Cardiometabolic-Based Chronic Disease in the Czech Population: Biological, Behavioral, and Cultural/Social Determinants of Health.

Autor:	Pavlovska I; International Clinical Research Centre (ICRC), St Anne's University Hospital Brno (FNUSA), 65691 Brno, Czech Republic.; Department of Public Health, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic., Polcrova A; International Clinical Research Centre (ICRC), St Anne's University Hospital Brno (FNUSA), 65691 Brno, Czech Republic.; Research Centre for Toxic Compounds in the Environment (RECETOX), Masaryk University, 62500 Brno, Czech Republic., Mechanick JI; The Marie-Josée and Henry R. Kravis Center for Cardiovascular Health at Mount Sinai Heart, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA.; Division of Endocrinology, Diabetes and Bone Disease, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Brož J; Department of Internal Medicine, Charles University Second Faculty of Medicine, 10506 Prague, Czech Republic., Infante-Garcia MM; International Clinical Research Centre (ICRC), St Anne's University Hospital Brno (FNUSA), 65691 Brno, Czech Republic.; Foundation for Clinic, Public Health, and Epidemiology Research of Venezuela (FISPEVEN INC), Barquisimeto 3001, Lara, Venezuela., Nieto-Martínez R; Foundation for Clinic, Public Health, and Epidemiology Research of Venezuela (FISPEVEN INC), Barquisimeto 3001, Lara, Venezuela.; Department of Global Health and Population, Harvard TH Chan School of Public Health, Harvard University, Boston, MA 02115, USA.; LifeDoc Health, Memphis, TN 38119, USA., Maranhao Neto GA; International Clinical Research Centre (ICRC), St Anne's University Hospital Brno (FNUSA), 65691 Brno, Czech Republic., Kunzova S; International Clinical Research Centre (ICRC), St Anne's University Hospital Brno (FNUSA), 65691 Brno, Czech Republic., Skladana M; International Clinical Research Centre (ICRC), St Anne's University Hospital Brno (FNUSA), 65691 Brno, Czech Republic.; Second Department of Internal Medicine, St. Anne's University Hospital in Brno and Faculty of Medicine, Masaryk University, 65691 Brno, Czech Republic., Novotny JS; International Clinical Research Centre (ICRC), St Anne's University Hospital Brno (FNUSA), 65691 Brno, Czech Republic., Pikhart H; Research Centre for Toxic Compounds in the Environment (RECETOX), Masaryk University, 62500 Brno, Czech Republic.; Department of Epidemiology and Public Health, University College London, London WC1E6BT, UK., Urbanová J; Center for Research in Diabetes, Metabolism and Nutrition, Second Department of Internal Medicine, Third Faculty of Medicine, University Hospital Královské Vinohrady, 10000 Prague, Czech Republic., Stokin GB; International Clinical Research Centre (ICRC), St Anne's University Hospital Brno (FNUSA), 65691 Brno, Czech Republic., Medina-Inojosa JR; Division of Preventive Cardiology, Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN 55905, USA.; Marriott Heart Disease Research Program, Mayo Clinic, Rochester, MN 55905, USA., Vysoky R; Department of Public Health, Faculty of Medicine, Masaryk University, 62500 Brno, Czech Republic.; Department of Health Support, Faculty of Sport Studies, Masaryk University, 62500 Brno, Czech Republic., González-Rivas JP; International Clinical Research Centre (ICRC), St Anne's University Hospital Brno (FNUSA), 65691 Brno, Czech Republic.; Foundation for Clinic, Public Health, and Epidemiology Research of Venezuela (FISPEVEN INC), Barquisimeto 3001, Lara, Venezuela.; Department of Global Health and Population, Harvard TH Chan School of Public Health, Harvard University, Boston, MA 02115, USA.
Jazyk:	angličtina
Zdroj:	Nutrients [Nutrients] 2021 Jul 08; Vol. 13 (7). Date of Electronic Publication: 2021 Jul 08.
DOI:	10.3390/nu13072338
Abstrakt:	In contrast to the decreasing burden related to cardiovascular disease (CVD), the burden related to dysglycemia and adiposity complications is increasing in Czechia, and local drivers must be identified. A comprehensive literature review was performed to evaluate biological, behavioral, and environmental drivers of dysglycemia and abnormal adiposity in Czechia. Additionally, the structure of the Czech healthcare system was described. The prevalence of obesity in men and diabetes in both sexes has been increasing over the past 30 years. Possible reasons include the Eastern European eating pattern, high prevalence of physical inactivity and health illiteracy, education, and income-related health inequalities. Despite the advanced healthcare system based on the compulsory insurance model with free-for-service healthcare and a wide range of health-promoting initiatives, more effective strategies to tackle the adiposity/dysglycemia are needed. In conclusion, the disease burden related to dysglycemia and adiposity in Czechia remains high but is not translated into greater CVD. This discordant relationship likely depends more on other factors, such as improvements in dyslipidemia and hypertension control. A reconceptualization of abnormal adiposity and dysglycemia into a more actionable cardiometabolic-based chronic disease model is needed to improve the approach to these conditions. This review can serve as a platform to investigate causal mechanisms and secure effective management of cardiometabolic-based chronic disease.
Databáze:	MEDLINE
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