[Research advances of studies on involvement of the anterior cingulate cortex involved in acupuncture-induced amelioration treatment of affective pain].

Autor: Liu LM; Department of Acupuncture and Moxibustion, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China; School of Acupuncture-moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai 201203., Hou YC; Department of Acupuncture and Moxibustion, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 200437, China; School of Acupuncture-moxibustion and Tuina, Shanghai University of Traditional Chinese Medicine, Shanghai 201203., Chen YL; Department of Orthopedics, Shanghai Guanghua Hospital of Integrated Chinese and Western Medicine, Shanghai 200052.
Jazyk: čínština
Zdroj: Zhen ci yan jiu = Acupuncture research [Zhen Ci Yan Jiu] 2021 Jul 25; Vol. 46 (7), pp. 620-4.
DOI: 10.13702/j.1000-0607.200929
Abstrakt: As an unpleasant subjective feeling and emotional experience, pain has a negative impact on the physical and mental health of patients. In the early years, the research concerning pain mostly focused on the sensory-discriminative component. With the development of modern medicine, people found that the generation of affective-emotional component of pain has its unique physiological mechanism, and thus carried out a lot of in-depth research. The anterior cingulate cortex (ACC) is the main brain area activated by affective pain, and the regulation of acupuncture on pain aversion is mainly related to it. The mechanism includes various signal pathways, such as extracellular regulated protein kinases-mitogen activated protein kinase-cAMP-response element binding protein pathway, adenylate cyclase 1 protein kinase Mζ- glutamate receptor 1 pathway, contains many biomolecules, such as opioid receptors, neuropeptide S and its receptor, and refers to microglia at the cellular level. This article reviewed the neural mechanism of ACC involved in affective pain and the role of acupuncture played in this process.
Databáze: MEDLINE