Larger cells have relatively smaller nuclei across the Tree of Life.

Autor: Malerba ME; Centre of Geometric Biology, School of Biological Sciences Monash University Melbourne Australia.; Centre for Integrative Ecology, School of Life and Environmental Sciences Deakin University Victoria Australia., Marshall DJ; Centre of Geometric Biology, School of Biological Sciences Monash University Melbourne Australia.
Jazyk: angličtina
Zdroj: Evolution letters [Evol Lett] 2021 Jun 29; Vol. 5 (4), pp. 306-314. Date of Electronic Publication: 2021 Jun 29 (Print Publication: 2021).
DOI: 10.1002/evl3.243
Abstrakt: Larger cells have larger nuclei, but the precise relationship between cell size and nucleus size remains unclear, and the evolutionary forces that shape this relationship are debated. We compiled data for almost 900 species - from yeast to mammals - at three scales of biological organisation: among-species, within-species, and among-lineages of a species that was artificially selected for cell size. At all scales, we showed that the ratio of nucleus size to cell size (the 'N: C' ratio) decreased systematically in larger cells. Size evolution appears more constrained in nuclei than cells: cell size spans across six orders of magnitude, whereas nucleus size varies by only three. The next important challenge is to determine the drivers of this apparently ubiquitous relationship in N:C ratios across such a diverse array of organisms.
(© 2021 The Authors. Evolution Letters published by Wiley Periodicals LLC on behalf of Society for the Study of Evolution (SSE) and European Society for Evolutionary Biology (ESEB).)
Databáze: MEDLINE
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