Patients with COVID-19-associated olfactory impairment also show impaired trigeminal function.

Autor: Otte MS; Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Medical Faculty, Cologne 50924, Germany. Electronic address: martin.otte@uk-koeln.de., Bork ML; Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Medical Faculty, Cologne 50924, Germany., Zimmermann PH; Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Medical Faculty, Cologne 50924, Germany., Klußmann JP; Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Medical Faculty, Cologne 50924, Germany; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Faculty of Medicine and University Hospital Cologne, Cologne, Germany., Lüers JC; Department of Otorhinolaryngology, Head and Neck Surgery, University of Cologne, Medical Faculty, Cologne 50924, Germany.
Jazyk: angličtina
Zdroj: Auris, nasus, larynx [Auris Nasus Larynx] 2022 Feb; Vol. 49 (1), pp. 147-151. Date of Electronic Publication: 2021 Jul 26.
DOI: 10.1016/j.anl.2021.07.012
Abstrakt: Objective: Next to olfactory function, the nose can also perceive chemestetic sensations mediated by the trigeminal nerve. While olfactory dysfunction as a symptom of COVID-19 is well described, there has been little research on the limitation of other nasal sensory inputs due to SARS-CoV-2 infection. The aim of this study was to determine possible limitations of nasal chemesthesis after COVID-19 infection by a psychophysiological diagnostic tool.
Methods: In 65 patients with a PCR-confirmed, former COVID-19 disease, olfaction was tested by means of a sniffin' sticks test, tasting by taste sprays and chemesthesis with a menthol dilution series. The subjective self-assessment of the patients was recorded via a questionnaire.
Results: We found a restriction of nasal chemesthesis and the extent correlated with the loss of smell, as well as with the values of the taste score, but not with subjective self-assessment.
Conclusion: Not only the ability to smell and taste, but also nasal chemesthesis is affected by COVID-19.
Competing Interests: Declaration of Competing interest The authors received no external funding for this work and declare no conflicts of interest or competing interests.
(Copyright © 2021 Japanese Society of Otorhinolaryngology-Head and Neck Surgery, Inc. Published by Elsevier B.V. All rights reserved.)
Databáze: MEDLINE
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