Results of childhood glaucoma surgery over a long-term period.

Autor: Hoffmann EM; Childhood Glaucoma Center, Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany., Aghayeva F; Childhood Glaucoma Center, Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany.; National Centre of Ophthalmology Named After Academician Zarifa Aliyeva, Baku, Aserbaidschan., Schuster AK; Childhood Glaucoma Center, Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany., Pfeiffer N; Childhood Glaucoma Center, Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany., Karsten M; Childhood Glaucoma Center, Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany., Schweiger S; Institute of Human Genetics, University Medical Center Mainz, Mainz, Germany., Pirlich N; Department of Anesthesiology, University Medical Center Mainz, Mainz, Germany., Wagner FM; Childhood Glaucoma Center, Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany., Chronopoulos P; Childhood Glaucoma Center, Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany., Grehn F; Childhood Glaucoma Center, Department of Ophthalmology, University Medical Center Mainz, Mainz, Germany.
Jazyk: angličtina
Zdroj: Acta ophthalmologica [Acta Ophthalmol] 2022 Mar; Vol. 100 (2), pp. e448-e454. Date of Electronic Publication: 2021 Aug 06.
DOI: 10.1111/aos.14985
Abstrakt: Purpose: To evaluate long-term results of glaucoma surgery in newborn and infants with glaucoma.
Methods: Seventy-nine eyes of 52 children (age: 3 weeks-15.3 years) with primary congenital or secondary glaucoma treated between 2015 and 2017 were included. The median follow-up time was 3.9 years. Conventional probe trabeculotomy, 360° catheter-assisted trabeculotomy, filtering and cyclodestructive surgery were compared. Strict criteria for surgical success were applied: Complete surgical success (IOP below target IOP, no further surgery) and incomplete surgical success (additional surgery allowed) were analyzed, and IOP at baseline and last follow-up was compared.
Results: Intraocular pressure (IOP) was significantly reduced in primary congenital (preoperative IOP: 27.8 ± 7.5 mmHg vs. postoperative IOP: 14.2 ± 4.5 mmHg) and secondary glaucoma (preoperative IOP: 29.2 ± 9.1 mmHg vs. postoperative IOP: 16.6 ± 4.7 mmHg). 90% of all eyes reached target IOP with or without medication allowing for additional surgeries. As first surgery, 360° catheter-assisted trabeculotomy had a tendency to higher surgical success than other surgical approaches, while cyclodestructive procedures had lowest.
Conclusions: We found very promising surgical results in our childhood glaucoma patient group. Surgical success in both congenital and secondary glaucoma was high.
(© 2021 The Authors. Acta Ophthalmologica published by John Wiley & Sons Ltd on behalf of Acta Ophthalmologica Scandinavica Foundation.)
Databáze: MEDLINE
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