| Autor: |
Riegler TF; Berner Reha Zentrum AG, Heiligenschwendi, Switzerland.; Institute for Physiotherapy, Zurich University of Applied Sciences, Zurich, Switzerland., Frei A; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland., Haile SR; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland., Radtke T; Epidemiology, Biostatistics and Prevention Institute, University of Zurich, Zurich, Switzerland. |
| Jazyk: |
angličtina |
| Zdroj: |
ERJ open research [ERJ Open Res] 2021 Aug 02; Vol. 7 (3). Date of Electronic Publication: 2021 Aug 02 (Print Publication: 2021). |
| DOI: |
10.1183/23120541.00921-2020 |
| Abstrakt: |
The aim of this study was to determine if there is a difference in 6-min walk test (6MWT) distance when the assessor accompanies the patient to continuously measure peripheral oxygen saturation ( S pO 2 ) compared to the patient walking unaccompanied. We conducted a randomised crossover study to evaluate the impact of the assessor walking with the patient during the 6MWT (6MWT with ) versus the patient walking alone (6MWT without ). At the end of a pulmonary rehabilitation programme, each patient performed two 6MWTs in random order and separated by a 30-min rest. 49 patients with chronic obstructive pulmonary disease (COPD) (Global Initiative for Obstructive Lung Disease classification II-IV) were included. In a regression model adjusting for period and subject, accompanying the patient resulted in a lower walking distance (mean difference -9.1 m, 95% CI -13.9- -4.3, p=0.0004). Notably, six patients walked more than 30 m farther (minimal important difference) in one of the two conditions (6MWT with : n=1, 6MWT without : n=5). There were no between-sequence-group differences in heart rate, dyspnoea, leg fatigue and S pO 2 . The median (interquartile range) number and duration of S pO 2 signal artefacts were high but not different between the experimental conditions (6MWT with : 17 (4-24), 34 s (7-113 s); 6 MWT without : 11 (3-26), 24 s (4-62 s)). At a study population level, we observed a statistically significant difference in 6MWT distance between the two experimental conditions; however, the magnitude of difference was small and may not be clinically relevant. Nevertheless, in a clinical setting, unaccompanied walking resulted in a substantially higher walking distance in individual patients, pointing towards strictly standardised testing methodology, in particular in pre-post study designs.
Competing Interests: Conflict of interest: T.F. Riegler has nothing to disclose. Conflict of interest: A. Frei has nothing to disclose. Conflict of interest: S.R. Haile has nothing to disclose. Conflict of interest: T. Radtke has nothing to disclose.
(Copyright ©The authors 2021.) |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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