Comparison of End-Tidal Anesthetic Gas Concentration versus Bispectral Index-Guided Protocol as Directing Tool on Time to Tracheal Extubation for Sevoflurane-Based General Anesthesia.

Autor: Shukla U; Department of Anaesthesiology, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India., Yadav U; Department of Anaesthesiology, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India., Yadav JBS; Department of Anaesthesiology, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India., Agrawal S; Department of Anaesthesiology, Uttar Pradesh University of Medical Sciences, Saifai, Etawah, Uttar Pradesh, India.
Jazyk: angličtina
Zdroj: Anesthesia, essays and researches [Anesth Essays Res] 2020 Oct-Dec; Vol. 14 (4), pp. 600-604. Date of Electronic Publication: 2021 May 27.
DOI: 10.4103/aer.AER_25_21
Abstrakt: Background: Modalities for titrating anesthetic drug-like bispectral index (BIS) and end-tidal anesthetic gas (ETAG) concentration in predicting early extubation had been studied with old anesthetic agents such as isoflurane.
Aim: The aim of this study is to compare the effect of ETAG concentration versus BIS-guided protocol as directing tool on time to tracheal extubation for sevoflurane-based general anesthesia.
Materials and Methods: This prospective, randomized, double-blind trial studied sixty patients with American Society of Anesthesiologists physical status classes I and II who received sevoflurane-based general anesthesia and were allocated to either BIS-guided anesthesia group ( n = 30) or ETAG-guided anesthesia group ( n = 30). Time to tracheal extubation was measured. BIS value was kept between 40 and 60 in BIS group, whereas minimum alveolar concentration value was kept between 0.7 and 1.3 in ETAG group. The two groups were compared using Student's t -test, and P < 0.05 was considered statistically significant. The statistical analysis was performed using the open source "R" programming language.
Results: Mean time to tracheal extubation was significantly shorter in BIS group (308.77 ± 20.48 s) as compared to ETAG group (377.90 ± 25.06 s) ( P < 0.001). The sevoflurane concentration used was also significantly less in group BIS than group ETAG at multiple time intervals ( P = 0.001).
Conclusion: Prediction of extubation was significantly early with BIS monitoring as compared to ETAG monitoring in sevoflurane-based general anesthesia.
Competing Interests: There are no conflicts of interest.
(Copyright: © 2021 Anesthesia: Essays and Researches.)
Databáze: MEDLINE
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