Voiding dysfunction in children causes, management, and prognosis: A single-center retrospective study.

Autor:	El Desoky SM; From the Department of Pediatrics (El Desoky, Zaher, Kari); from the Paediatric Nephrology Center of Excellence (El Desoky, Kari); from the Department of Urology (Banakhar); and from the Department of Radiology (Khashoggi), Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia., Banakhar M; From the Department of Pediatrics (El Desoky, Zaher, Kari); from the Paediatric Nephrology Center of Excellence (El Desoky, Kari); from the Department of Urology (Banakhar); and from the Department of Radiology (Khashoggi), Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia., Khashoggi K; From the Department of Pediatrics (El Desoky, Zaher, Kari); from the Paediatric Nephrology Center of Excellence (El Desoky, Kari); from the Department of Urology (Banakhar); and from the Department of Radiology (Khashoggi), Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia., Zaher ZF; From the Department of Pediatrics (El Desoky, Zaher, Kari); from the Paediatric Nephrology Center of Excellence (El Desoky, Kari); from the Department of Urology (Banakhar); and from the Department of Radiology (Khashoggi), Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia., Kari JA; From the Department of Pediatrics (El Desoky, Zaher, Kari); from the Paediatric Nephrology Center of Excellence (El Desoky, Kari); from the Department of Urology (Banakhar); and from the Department of Radiology (Khashoggi), Faculty of Medicine, King Abdulaziz University, Jeddah, Kingdom of Saudi Arabia.
Jazyk:	angličtina
Zdroj:	Saudi medical journal [Saudi Med J] 2021 Aug; Vol. 42 (8), pp. 869-877.
DOI:	10.15537/smj.2021.42.8.20210327
Abstrakt:	Objectives: To review voiding dysfunction caused by 3 different etiologies; dysfunction voiding syndrome (DVS), neurogenic bladder secondary to spinal dysraphisim (NB), and valve bladder syndrome (VBS). Methods: A single-center retrospective study on children with voiding dysfunction followed up at King Abdulaziz University Hospital, Jeddah, Saudi Arabia from 2005 to 2017. Results: One hundred and ninety-nine children (67.3% boys) were included: Group 1 (n=75, DVS), Group 2 (n=64, NB), and Group 3 (n=60, VBS). Further classification according to the age at presentation; infants (46%), toddlers (27%) and school aged (28%). Management categories: 31% children needed observation only, 25% needed clean intermittent catheterization (CIC), 13% needed only surgery and 31% needed both surgery and CIC. Associated comorbidities: hydronephrosis (81%), vesicoureteral reflux (47%), pyelonephritis (37%) and renal scar (60%), all have negative impact on estimated glomerular filtration rate (eGFR). Urodynamic studies revealed poor bladder compliance in 57.6% and atonic bladder in 1.1%, progression to chronic kidney disease (22%), commenced on renal replacement therapy 11.5% and 4% died with ESKD. Overall improvement in the last eGFR is observed ( p <0.001), but VBS group was the least to improve ( p =0.021). There was a negative correlation between the last eGFR and age at presentation (p=0.002). Conclusion: Early diagnosis and management of childhood voiding dysfunction was associated with better prognosis. Children managed conservatively have better preservation of kidney function than those who needed surgery. (Copyright: © Saudi Medical Journal.)
Databáze:	MEDLINE
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