| Autor: |
Hong Nguyen TA; Department of Chemistry, National Central University, No. 300 Jhong-Da Road, Jhong-li, Taoyuan Taiwan 32001., Hou DR; Department of Chemistry, National Central University, No. 300 Jhong-Da Road, Jhong-li, Taoyuan Taiwan 32001. |
| Jazyk: |
angličtina |
| Zdroj: |
Organic letters [Org Lett] 2021 Nov 05; Vol. 23 (21), pp. 8127-8131. Date of Electronic Publication: 2021 Aug 03. |
| DOI: |
10.1021/acs.orglett.1c02183 |
| Abstrakt: |
Acetoxylation of arenes is an important reaction and an unmet need in chemistry. We report a metal-free, direct acetoxylation reaction using sodium nitrate under an anhydrous environment of trifluoroacetic acid, acetic acid, and acetic anhydride. Arenes (31 examples), with oxidation potentials ( E ox , in V vs SCE) lower than benzene (2.48 V), were acetoxylated with good yields and regioselectivity. A stepwise, single electron-transfer mechanism is proposed. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
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