Substantial and Reproducible Individual Variability in Skeletal Muscle Outcomes in the Cross-Over Designed Planica Bed Rest Program.
Autor: | Fernandez-Gonzalo R; Department of Laboratory Medicine, Division of Clinical Physiology, Karolinska Institutet, and Unit of Clinical Physiology, Karolinska University Hospital, Stockholm, Sweden., McDonnell AC; Department of Automation, Biocybernetics and Robotics, Jozef Stefan Institute, Ljubljana, Slovenia., Simpson EJ; MRC Arthritis Research UK Centre for Musculoskeletal Ageing Research, School of Life Sciences, University of Nottingham Medical School, Nottingham, United Kingdom., Macdonald IA; MRC Arthritis Research UK Centre for Musculoskeletal Ageing Research, School of Life Sciences, University of Nottingham Medical School, Nottingham, United Kingdom., Rullman E; Department of Laboratory Medicine, Division of Clinical Physiology, Karolinska Institutet, and Unit of Clinical Physiology, Karolinska University Hospital, Stockholm, Sweden., Mekjavic IB; Department of Automation, Biocybernetics and Robotics, Jozef Stefan Institute, Ljubljana, Slovenia.; Department of Biomedical Physiology and Kinesiology, Simon Fraser University, Burnaby, BC, Canada. |
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Jazyk: | angličtina |
Zdroj: | Frontiers in physiology [Front Physiol] 2021 Jul 16; Vol. 12, pp. 676501. Date of Electronic Publication: 2021 Jul 16 (Print Publication: 2021). |
DOI: | 10.3389/fphys.2021.676501 |
Abstrakt: | To evaluate the individual responses in skeletal muscle outcomes following bed rest, data from three studies (21-day PlanHab; 10-day FemHab and LunHab) were combined. Subjects ( n = 35) participated in three cross-over campaigns within each study: normoxic (NBR) and hypoxic bed rest (HBR), and hypoxic ambulation (HAMB; used as control). Individual variability (SD Competing Interests: The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. (Copyright © 2021 Fernandez-Gonzalo, McDonnell, Simpson, Macdonald, Rullman and Mekjavic.) |
Databáze: | MEDLINE |
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