Solid-phase extraction of alkylphosphonic and O-alkyl alkylphosphonic acids followed by HPLC separation using porous graphitic carbon sorbent.

Autor: Goncharova EN; Department of Chemistry, Lomonosov Moscow State University, 1-3 Leninskie Gory, GSP-3, Moscow 119991, Russian Federation., Statkus MA; Department of Chemistry, Lomonosov Moscow State University, 1-3 Leninskie Gory, GSP-3, Moscow 119991, Russian Federation. Electronic address: mstatkus@gmail.com., Nesterenko PN; Department of Chemistry, Lomonosov Moscow State University, 1-3 Leninskie Gory, GSP-3, Moscow 119991, Russian Federation., Tsysin GI; Department of Chemistry, Lomonosov Moscow State University, 1-3 Leninskie Gory, GSP-3, Moscow 119991, Russian Federation., Zolotov YA; Department of Chemistry, Lomonosov Moscow State University, 1-3 Leninskie Gory, GSP-3, Moscow 119991, Russian Federation; Kurnakov Institute of General and Inorganic Chemistry, Russian Academy of Sciences, Leninsky Prospect, 31-1, Moscow 119991, Russian Federation.
Jazyk: angličtina
Zdroj: Journal of chromatography. A [J Chromatogr A] 2021 Sep 13; Vol. 1653, pp. 462420. Date of Electronic Publication: 2021 Jul 22.
DOI: 10.1016/j.chroma.2021.462420
Abstrakt: An HPLC separation of alkyl phosphonic acids on porous graphitic carbon adsorbent Hypercarb, based upon a step gradient of formic acid concentration in an aqueous mobile phase, was evaluated in this study. Analytes were detected by single quadrupole and triple quadrupole MS. Good separation was achieved for methyl phosphonic acid, ethylphosphonic acid, n-propylphosphonic acid, isopropylphosphonic acid, ethyl methylphosphonic acid, isopropyl methylphosphonic acid, isobutyl methylphosphonic acid, pinacolyl methylphosphonic acid. Solid-phase extraction of these analytes on Hypercarb was also proposed, desorption was carried out with aqueous ammonium formate and water-methanol mixtures. LODs were 0.1-0.2 ng mL-1 for these analytes without SPE; solid-phase extraction resulted in the decrease of LODs at least 100-fold. Accuracy was proven by analyses of spiked samples of river water and snow meltwater.
Competing Interests: Declaration of Competing Interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.
(Copyright © 2021. Published by Elsevier B.V.)
Databáze: MEDLINE
Externí odkaz: