Medullary Carcinoma of the Colon: A Histopathologic Challenge.

Autor: Fatima Z; Internal Medicine, East Tennessee State University, Johnson City, USA., Sharma P; Medical Oncology, East Tennessee State University, Johnson City, USA., Youssef B; Pathology, East Tennessee State University, Johnson City, USA., Krishnan K; Medical Oncology, East Tennessee State University, Johnson City, USA.
Jazyk: angličtina
Zdroj: Cureus [Cureus] 2021 Jun 22; Vol. 13 (6), pp. e15831. Date of Electronic Publication: 2021 Jun 22 (Print Publication: 2021).
DOI: 10.7759/cureus.15831
Abstrakt: Medullary carcinoma (MC) of the colon is a rare and unique histologic subtype of colorectal cancer. It is commonly associated with deficient mismatch repair proteins and has a strong association with Lynch syndrome. Diagnosis is challenging as it does not have the usual immunohistochemical stains on pathology seen in colorectal adenocarcinoma. Here, we discuss an interesting case of MC of the colon that was metastatic on presentation and constituted a diagnostic challenge.
Competing Interests: The authors have declared that no competing interests exist.
(Copyright © 2021, Fatima et al.)
Databáze: MEDLINE