Can Subclinical Atherosclerosis Be Assessed More Precisely in Behçet Syndrome Patients by Using a Particular Cutoff Value for Carotid Intima Media Thickness?

Autor:	Uslu Yurteri E; From the Departments of Rheumatology., Üstüner E; Radiology, Ankara University Faculty of Medicine, Ankara, Turkey., Torgutalp M; From the Departments of Rheumatology., Yayla ME; From the Departments of Rheumatology., Okatan IE; From the Departments of Rheumatology., Sezer S; From the Departments of Rheumatology., Keleşoğlu Dinçer AB; From the Departments of Rheumatology., Gülöksüz AEG; From the Departments of Rheumatology., Turgay TM; From the Departments of Rheumatology., Kinikli G; From the Departments of Rheumatology., Ateş A; From the Departments of Rheumatology.
Jazyk:	angličtina
Zdroj:	Journal of clinical rheumatology : practical reports on rheumatic & musculoskeletal diseases [J Clin Rheumatol] 2022 Jan 01; Vol. 28 (1), pp. e73-e76.
DOI:	10.1097/RHU.0000000000001643
Abstrakt:	Objective: Behçet syndrome (BS) is a multisystemic chronic vasculitic disease. Among previous studies, although there are some that showed increased risk of subclinical atherosclerosis in BS, there are also others that showed the opposite. The objective of this study is to evaluate subclinical atherosclerosis in BS by using the cutoff value for intima-media thickness in the 2013 European Society of Cardiology/European Society of Hypertension guideline. Methods: We conducted a cross-sectional analysis of 100 BS patients and 30 healthy volunteers at a single center in a 4-month period. All ultrasound scans were performed in a blind manner to the clinical assessment, and they were carried out by the same researcher by a B-mode ultrasonography. Result: When we grouped the patients based on the presence of subclinical atherosclerosis, the frequency of subclinical atherosclerosis in the BS patients was found to be higher than that in the healthy controls (32% and 7%, respectively; p = 0.006). When a cutoff is used for carotid intima-media thickness, increased atherosclerosis risk is observed in BS patients with vascular involvement (p = 0.043). Conclusions: Although higher inflammation and increased atherosclerosis in vascular BS patients were expected, this situation was not supported much in previous studies. We think that this may have been caused by mere comparison of numerical data, and usage of a cutoff value could be more significant in distinguishing what is normal and what is abnormal as in several medical parameters. Competing Interests: The authors declare no conflict of interest. (Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.)
Databáze:	MEDLINE
Externí odkaz:	Zobrazit plný text záznamu