| Autor: |
Montero-Cabezas JM; Department of Cardiology, Leiden University Medical Center, Leiden, the Netherlands., Córdoba-Soriano JG; Department of Cardiology, Complejo Hospitalario Universitario de Albacete, Albacete, Spain., Díez-Delhoyo F; Department of Cardiology, Instituto de Investigación Sanitaria Gregorio Marañón, Hospital General Universitario Gregorio Marañón, Madrid, Spain., Abellán-Huerta J; Department of Cardiology, Hospital General Universitario de Ciudad Real, Ciudad Real, Spain., Girgis H; Department of Cardiology, Jeroen Bosch Hospital. 's-Hertogenbosch, the Netherlands., Rama-Merchán JC; Department of Cardiology, Hospital de Mérida, Mérida, Spain., García-Blas S; Department of Cardiology, Hospital Clínico Universitario de Valencia, Valencia, Spain., van Rees JB; Department of Cardiology, Rijnstate Hospital, Arnhem, the Netherlands., van Ramshorst J; Department of Cardiology, Noordwest Ziekenhuisgroep, Alkmaar, the Netherlands., Jurado-Román A; Department of Cardiology, Hospital Universitario La Paz, Madrid, Spain. |
| Abstrakt: |
Data regarding angiographic characteristics, clinical profile, and inhospital outcomes of patients with coronavirus disease 2019 (COVID-19) referred for coronary angiography (CAG) are scarce. This is an observational study analyzing confirmed patients with COVID-19 referred for CAG from 10 European centers. We included 57 patients (mean age: 66 ± 15 years, 82% male) , of whom 18% had previous myocardial infarction (MI) and 29% had renal insufficiency and chronic pulmonary disease. ST-segment elevation myocardial infarction (STEMI) was the most frequent indication for CAG (58%). Coronavirus disease 2019 was confirmed after CAG in 86% and classified as mild in 49%, with 21% fully asymptomatic. A culprit lesion was identified in 79% and high thrombus burden in 42%; 7% had stent thrombosis. At 40 days follow-up, 16 (28%) patients experienced a major adverse cardiovascular event (MACE): 12 deaths (92% noncardiac), 1 MI, 2 stent thrombosis, and 1 stroke. In an European multicenter registry, patients with confirmed COVID-19 infection referred for CAG during the first wave of the severe acute respiratory syndrome coronavirus 2 pandemic presented mostly with STEMI and were predominantly males with comorbidities. Severity of COVID-19 was in general noncritical and 21% were asymptomatic at the time of CAG. Culprit coronary lesions with high thrombus burden were frequently identified, with a rate of stent thrombosis of 7%. The incidence of MACE at 40 days was high (28%), mostly due to noncardiac death. |
