Maternal Serum and Umbilical Cord Brain Natriuretic Peptide Levels in Fetuses with Intrauterine Growth Restriction.

Autor: Eroğlu H; Etlik Zübeyde Hanım Maternity and Women's Health Teaching and Research Hospital, Ankara, Turkey., Erdöl MA; Department of Cardiology, Ankara City Hospital, Ankara, Turkey., Tonyalı NV; Etlik Zübeyde Hanım Maternity and Women's Health Teaching and Research Hospital, Ankara, Turkey., Örgül G; Etlik Zübeyde Hanım Maternity and Women's Health Teaching and Research Hospital, Ankara, Turkey., Biriken D; Faculty of Medicine, Department of Microbiology, Ankara University, Ankara, Turkey., Yücel A; Etlik Zübeyde Hanım Maternity and Women's Health Teaching and Research Hospital, Ankara, Turkey., Yazihan N; Faculty of Medicine, Department of Pathophysiology, Ankara University, Ankara, Turkey., Şahin D; Etlik Zübeyde Hanım Maternity and Women's Health Teaching and Research Hospital, Ankara, Turkey.
Jazyk: angličtina
Zdroj: Fetal and pediatric pathology [Fetal Pediatr Pathol] 2022 Oct; Vol. 41 (5), pp. 722-730. Date of Electronic Publication: 2021 Jul 26.
DOI: 10.1080/15513815.2021.1955057
Abstrakt: Aim: We compared maternal serum and fetal cord blood proBNP levels in healthy pregnancies to those with intrauterine growth restriction (IUGR). Methods: Prospectively, maternal and cord blood samples at childbirth of 40 pregnant women with isolated IUGR and 40 healthy pregnant women were evaluated for ProBNP levels. Results: The mean serum ProBNP level was significantly higher in newborn cord blood with IUGR than in the control group (181.28 ± 145.37 vs. 91.41 ± 49.77 pg/mL, p = <0.01). Mean serum ProBNP level trended higher in women with IUGR compared to the controls, but was not statistically significant (124.21 ± 113.32 vs. 88.73 ± 85.18 pg/mL, p = >0.05). Conclusion: Third trimester mean proBNP in fetal cord blood are increased in IUGR fetuses at term birth compared to pregnancies with normal fetal growth.
Databáze: MEDLINE
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