Endocarditis Caused by Candida parapsilosis Presenting With Severe Thrombocytopenia in a Patient With Tetralogy of Fallot.

Autor: Freddo AM; Internal Medicine-Pediatrics Residency Program, University of Colorado, Aurora, CO, USA., Mathur S; Division of Infectious Diseases, School of Medicine, University of Colorado, Aurora, CO, USA., Dunlevy H; Division of Infectious Diseases, School of Medicine, University of Colorado, Aurora, CO, USA., Jaggers J; Department of Cardiothoracic Surgery, Children's Hospital Colorado, Aurora, CO, USA., Khanna A; Division of Cardiology, School of Medicine, University of Colorado, Aurora, CO, USA.
Jazyk: angličtina
Zdroj: World journal for pediatric & congenital heart surgery [World J Pediatr Congenit Heart Surg] 2022 Mar; Vol. 13 (2), pp. 245-247. Date of Electronic Publication: 2021 Jul 26.
DOI: 10.1177/21501351211008839
Abstrakt: Infective endocarditis (IE) occurs more frequently in individuals living with congenital heart disease, often with high morbidity and mortality. Although gram-positive bacterial infections commonly cause IE, prosthetic valves are a known risk factor for fungal IE. We report a case of prosthetic pulmonary valve Candida parapsilosis IE in a 58-year-old male with repaired tetralogy of Fallot. He presented with fatigue, petechiae, and hematochezia. He had severe thrombocytopenia from idiopathic/immune thrombocytopenia purpura, which resolved with steroids and immunoglobulin. Treatment with antifungals as well as a surgical pulmonary valve replacement resulted in recovery without relapse at greater than a year.
Databáze: MEDLINE