Blood-to-saliva glucose time lag in sedated healthy dogs.
| Autor: | Ioannou A; Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Phillips H; Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Keating S; Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Barger A; Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Lopez-Villalobos N; School of Agriculture and Environment, Massey University, Palmerston North, New Zealand., Wilson M; Crater Animal Clinic, Central Point, OR, USA., Dillonaire A; Veterinary Emergency Group, Clifton, NJ, USA., Silveston-Keith R; CTO Accessible Diagnostics, University of South Carolina, Columbia, SC, USA., Ambrisko TD; Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA., Gal A; Department of Veterinary Clinical Medicine, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, Urbana, IL, USA. |
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| Jazyk: | angličtina |
| Zdroj: | Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc [J Vet Diagn Invest] 2021 Nov; Vol. 33 (6), pp. 1147-1150. Date of Electronic Publication: 2021 Jul 23. |
| DOI: | 10.1177/10406387211035367 |
| Abstrakt: | The management of diabetes mellitus mandates measurement of blood glucose. Saliva offers an alternative to blood sampling, but measurement of the salivary glucose concentration is difficult, and the blood-to-saliva glucose time lag is uncertain. We aimed to determine the serum-saliva glucose time lag in the saliva of healthy dogs. The combined duct of the mandibular and sublingual salivary glands of 6 dogs was cannulated to collect saliva and prevent glucose degradation by oral bacteria. Following a 0.25 g/kg IV bolus of dextrose, paired serum-saliva samples were collected at baseline and in twelve 5-min blocks over 60 min. Serum and salivary glucose levels were analyzed with a linear mixed model for repeated measures with a compound symmetry error structure. Mean (±SD) saliva production was 10.3 ± 2.9 µL/kg/min, and the area under the curve (AUC |
| Databáze: | MEDLINE |
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