Comparison of Incidence of Myocardial Infarction in Patients With Rheumatoid Arthritis and Diabetes Mellitus.

Autor:	Ali A; Internal Medicine, Mayo Hospital, Lahore, PAK., Ali A; Pulmonology and Critical Care, Services Hospital, Lahore, PAK., Kumar D; Internal Medicine, Western Michigan University, Kalamazoo, USA., Kumar R; Internal Medicine, Chandka Medical College, Larkana, PAK., Elahi K; Internal Medicine, Jinnah Postgraduate Medical Centre, Karachi, PAK., Suman F; Internal Medicine, Peoples University of Medical and Health Sciences for Women, Nawabshah, PAK., Anjum Z; Internal Medicine, Fatima Jinnah Medical University, Lahore, PAK., Tharwani P; Oral Medicine, Isra University, Hyderabad, PAK., Jahangir M; Internal Medicine, Dow, Medical College, Dow University of Health Sciences, Karachi, PAK., Rizwan A; Family Medicine, Jinnah Postgraduate Medical Centre, Karachi, PAK.
Jazyk:	angličtina
Zdroj:	Cureus [Cureus] 2021 Jun 17; Vol. 13 (6), pp. e15716. Date of Electronic Publication: 2021 Jun 17 (Print Publication: 2021).
DOI:	10.7759/cureus.15716
Abstrakt:	Introduction Patients with rheumatoid arthritis (RA) have a higher risk of cardiovascular diseases (CVDs) when compared to the general population, with most deaths attributed to myocardial infarctions (MI). However, patients with RA do not get the same attention in terms of cardiovascular screening as compared to other diseases, like diabetes mellitus (DM). Therefore, this study aims to compare the risk of CVD among patients with RA and DM. Methods This prospective study was carried out in Pakistan's two tertiary care hospitals. A total of 750 participants were enrolled in three groups with a 1:1:1 ratio; patients with RA, type 2 DM, and the control group. Patients were observed for 12 months or until the development of a major adverse cardiovascular event (MACE), whichever occurred first. Results Both fatal (12.66% vs. 13.48%; p-value: 0.79) and non-fatal (3.93% vs. 4.35%; p-value: 0.82) MI was comparable between both RA and DM group. However, compared to the control group, non-fatal MI (12.66% vs. 5.58%; p-value: 0.01) was significantly higher in the RA group. Conclusion Our study shows that RA and DM have an equal risk of cardiovascular (CV) events. It is important that RA should be considered as a prominent risk factor for CV events. The management of these patients should be multidisciplinary, including cardiologists. Competing Interests: The authors have declared that no competing interests exist. (Copyright © 2021, Ali et al.)
Databáze:	MEDLINE
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