Validation of the Mini-Addenbrooke's Cognitive Examination in Mild Cognitive Impairment in Arabic Speakers.

Autor:	Qassem T; Maudsley Health, Al-Amal Psychiatric Hospital, Dubai, United Arab Emirates.; Neuropsychiatry Department, Okasha Institute of Psychiatry, Ain Shams University, Cairo, Egypt.; Ministry of Health and Prevention (MOHAP), Al-Amal Psychiatric Hospital, Dubai, United Arab Emirates., Khater MS; Geriatrics and Gerontology Department, Ain Shams University, Cairo, Egypt., Emara T; Neurology Department, Ain Shams University, Cairo, Egypt., Rasheedy D; Geriatrics and Gerontology Department, Ain Shams University, Cairo, Egypt., Tawfik HM; Geriatrics and Gerontology Department, Ain Shams University, Cairo, Egypt., Mohammedin AS; Geriatrics and Gerontology Department, Ain Shams University, Cairo, Egypt.; Geriatrics and Gerontology Department, Imam Abdulrahman Bin Faisal University, Dammam, Saudi Arabia., Tolba MF; Geriatrics and Gerontology Department, Ain Shams University, Cairo, Egypt., Aly El-Gabry D; Neuropsychiatry Department, Okasha Institute of Psychiatry, Ain Shams University, Cairo, Egypt., Abdel Aziz K; Department of Psychiatry, College of Medicine and Health Sciences, United Arab Emirates University, Al-Ain, United Arab Emirates., Saber HG; Geriatrics and Gerontology Department, Ain Shams University, Cairo, Egypt.
Jazyk:	angličtina
Zdroj:	Dementia and geriatric cognitive disorders [Dement Geriatr Cogn Disord] 2021; Vol. 50 (2), pp. 178-182. Date of Electronic Publication: 2021 Jul 22.
DOI:	10.1159/000517580
Abstrakt:	Introduction: Mild cognitive impairment (MCI) represents a target for early detection and intervention in dementia, yet there is a shortage of validated screening tools in Arabic to diagnose MCI. The mini-Addenbrooke's Cognitive Examination (m-ACE) is a brief cognitive battery that is scored out of 30 and can be administered in under 5 min providing a quick screening tool for assessment of cognition. Objective: We aimed to validate the m-ACE in Arabic speakers in Egypt with MCI to provide cut-off scores. Methods: We included 24 patients with MCI and 52 controls and administered the Arabic version of the m-ACE. Results: There was a statistically significant difference (p < 0.0001) on the total m-ACE score between MCI patients (mean 18.54, SD 3.05) and controls (mean 24.54, SD 2.68). There was also a statistically significant difference between MCI patients and controls on the total score and the fluency, visuospatial, and memory recall sub-scores of the m-ACE (p < 0.05). Performance on the m-ACE significantly correlated with both the Mini-Mental State Examination (MMSE) and the Addenbrooke's Cognitive Examination-III (ACE-III). Using a receiver operator characteristic curve, the optimal cut-off score for MCI on the m-ACE total score was 21 out of 30 (87.5% sensitivity, 84.6% specificity, and 85.5% accuracy). Conclusions: We validated the Arabic m-ACE in Egyptian patients with MCI and provided objective validation of it as a screening tool for MCI, with good sensitivity, specificity, and accuracy that is comparable to other translated versions of the m-ACE in MCI. (© 2021 S. Karger AG, Basel.)
Databáze:	MEDLINE
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