Effects of Treatment of Coronavirus Disease 2019 With Convalescent Plasma in 25 B-Cell-Depleted Patients.

Autor:	Gharbharan A; Department of Internal Medicine, Section of Infectious Diseases and Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands., GeurtsvanKessel CH; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands., Jordans CCE; Department of Internal Medicine, Section of Infectious Diseases and Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands., Blaauw M; Department of Internal Medicine, Elisabeth-Tweesteden Hospital, Tilburg, The Netherlands., van der Klift M; Department of Internal Medicine, Amphia Hospital, Breda, The Netherlands., Hassing RJ; Department of Internal Medicine, Rijnstate Hospital, Arnhem, The Netherlands., Smits-Zwinkels M; Department of Pulmonary Medicine, ZorgSaam Hospital, Terneuzen, The Netherlands., Meertens M; Department of Intensive Care Medicine, Onze Lieve Vrouwe Gasthuis, Amsterdam, The Netherlands., van den Hout EC; Department of Internal Medicine, Northwest Clinics, Alkmaar, The Netherlands., de Man AM; Department of Internal Medicine, Elkerliek Ziekenhuis, Helmond, The Netherlands., Hageman I; Department of Internal Medicine, Jeroen Bosch Hospital, den Bosch, The Netherlands., Bogers S; Department of Viroscience, Erasmus Medical Center, Rotterdam, The Netherlands., van der Schoot CE; Department of Experimental Immunohematology, Sanquin Research, Amsterdam, The Netherlands., Swaneveld F; Unit of Transfusion Medicine, Sanquin Blood Supply, Amsterdam, The Netherlands., Anas AA; Department of Internal Medicine, Section of Infectious Diseases and Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands., Rokx C; Department of Internal Medicine, Section of Infectious Diseases and Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands., Rijnders BJA; Department of Internal Medicine, Section of Infectious Diseases and Department of Medical Microbiology and Infectious Diseases, Erasmus Medical Center, University Medical Center, Rotterdam, The Netherlands.
Jazyk:	angličtina
Zdroj:	Clinical infectious diseases : an official publication of the Infectious Diseases Society of America [Clin Infect Dis] 2022 Apr 09; Vol. 74 (7), pp. 1271-1274.
DOI:	10.1093/cid/ciab647
Abstrakt:	Twenty-five B-cell-depleted patients (24 following anti-CD19/20 therapy) diagnosed with coronavirus disease 2019 had been symptomatic for a median of 26 days but remained antibody negative. All were treated with convalescent plasma with high neutralizing antibody titers. Twenty-one (84%) recovered, indicating the potential therapeutic effects of this therapy in this particular population. (© The Author(s) 2021. Published by Oxford University Press for the Infectious Diseases Society of America.)
Databáze:	MEDLINE
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