The effect of Fasting during Ramadan on the Kidney functions of Stage III-IV Chronic Kidney Disease Patients.

Autor: Karatas A; Dr. Ahmet Karatas, MD. Nephrologist, Associated Professor, Department of Internal Medicine, Division of Neprology, Education and Research Hospital, Ordu University School of Medicine, Ordu, Turkey., Canakci E; Dr. Ebru Canakci, MD, Anesthesiologist, Associate Professor, Department of Anesthesiology and Reanimation, Education and Research Hospital, Ordu University School of Medicine, Ordu, Turkey., Arici YK; Dr. Yeliz Kasko Arici, PhD. Biostatistics Specialist, Assistant Professor, Department of Biostatistics and Medical Informatics, Ordu University School of Medicine, Ordu, Turkey., Kaya M; Mervegul Kaya, MD, Family Medicine Specialist, Attending Physician, Department of Family Medicine, Education and Research Hospital, Ordu University School of Medicine, Ordu, Turkey., Sayim B; Beyza Sayim, MD, Researcher Fellow Department of Internal Medicine, Education and Research Hospital, Ordu University School of Medicine, Ordu, Turkey.
Jazyk: angličtina
Zdroj: Pakistan journal of medical sciences [Pak J Med Sci] 2021 Jul-Aug; Vol. 37 (4), pp. 972-978.
DOI: 10.12669/pjms.37.4.3661
Abstrakt: Objectives: Examine the effect of fasting during Ramadan on kidney functions in patients with chronic kidney disease.
Methods: The study was conducted on 130 patients with stage III-IV chronic kidney disease (CKD), who were admitted to the Ordu University nephrology polyclinic during the month before Ramadan and one month after Ramadan in 2019. Blood samples were taken in the morning after 12 hours of fasting.
Results: There was a statistically significant difference between BUN in the fasting group before and after the month of Ramadan. The median BUN before Ramadan was 26.65 mg/dl, the median after Ramadan was 24.05 mg/dl (p=0.004).There was a statistically significant difference between the nonfasting groups before and after Ramadan with respect to creatinine level. Median creatinine before Ramadan was 1.69 mg/dl,and the median after Ramadan was 1.86 mg/dl (p <0.001).There was a statistically significant difference between the fasting groups before and after Ramadan with respect to creatinine levels. Fasting group ,the median before Ramadan was 1.5 mg/dl, and the median after Ramadan was 1.42 mg/dl (p = 0.038).The impact of independent variable of fasting, using linear regression was found to be statistically significant (p post- <0.001). The eGFR was 14.826 points higher in those who fasted after Ramadan than in those who did not.
Conclusion: Fasting during the month of Ramadan does not deteriorate kidney functions and even leads to a moderate improvement in kidney functions. Taking these results into consideration, fasting may be advised for patients with stage III-IV CKD who want to fast and remain in stable condition.
Competing Interests: Conflict of Interest: None.
(Copyright: © Pakistan Journal of Medical Sciences.)
Databáze: MEDLINE
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