Accelerating towards human African trypanosomiasis elimination: Issues and opportunities.

Autor: Ozioko KU; Department of Zoology and Environmental Biology, University of Nigeria, Nsukka, Nigeria., Okoye CI; Department of Zoology and Environmental Biology, University of Nigeria, Nsukka, Nigeria., Obiezue RN; Department of Zoology and Environmental Biology, University of Nigeria, Nsukka, Nigeria., Idika IK; Department of Veterinary Parasitology and Entomology, University of Nigeria, Nsukka, Nigeria., Awudu RA; Central Laboratory Unit, Federal University Wukari, Wukari, Taraba State, Nigeria., Ezewudo BI; Department of Zoology, Nnamdi Azikiwe University, Akwa Anambra State, Nigeria., Ezea CO; Department of Biology, Federal University of Technology, Owerre, Imo State, Nigeria.
Jazyk: angličtina
Zdroj: Journal of vector borne diseases [J Vector Borne Dis] 2020 Apr-Jun; Vol. 57 (2), pp. 105-113.
DOI: 10.4103/0972-9062.310860
Abstrakt: Human African trypanosomiasis (HAT) has been an alarming global public health issue. The disease affects mainly poor and marginalized people in low-resource settings and is caused by two subspecies of haemoflagellate parasite, Trypanosoma brucei and transmitted by tsetse flies. Progress made in HAT control during the past decade has prompted increasing global dialogue on its elimination and eradication. The disease is targeted by the World Health Organization (WHO) for elimination as a public health problem by 2020 and to terminate its transmission globally by 2030, along-side other Neglected Tropical Diseases (NTD). Several methods have been used to control tsetse flies and the disease transmitted by them. Old and new tools to control the disease are available with constraints. Currently, there are no vaccines available. Efforts towards intervention to control the disease over the past decade have seen considerable progress and remarkable success with incidence dropping progressively, reversing the upward trend of reported cases. This gives credence in a real progress in its elimination. This study reviews various control measures, progress and a highlight of control issues, vector and parasite barriers that may have been hindering progress towards its elimination.
Competing Interests: None
Databáze: MEDLINE