Spin Infrequently Occurs in Abstracts of Systematic Reviews For The Pharmacological Treatment of Type 2 Diabetes Mellitus.

Autor: Ottwell R; Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.; Department of Internal Medicine, University of Oklahoma, School of Community Medicine, Tulsa, OK, USA.; Samuel J. Wood Library & C.V. Starr Biomedical Information Center, Weill Cornell Medical College, New York, NY, USA., Esmond L; Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA., Rea W; Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.; Kansas City University of Medicine and Biosciences, Joplin, MO, USA., Hartwell M; Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.; Department of Psychiatry and Behavioral Sciences, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA., Som M; Department of Internal Medicine, Oklahoma State University Medical Center, Tulsa, OK, USA., Harris R; Department of Internal Medicine, Oklahoma State University Medical Center, Tulsa, OK, USA., Miao Z; Spears School of Business, Oklahoma State University, Stillwater, OK, USA., Zhu L; Department of Statistics, Oklahoma State University, Stillwater, OK, USA., Arthur W; Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA., Brachtenbach T; Department of Internal Medicine, Oklahoma State University Medical Center, Tulsa, OK, USA., Wright DN; Spears School of Business, Oklahoma State University, Stillwater, OK, USA., Vassar M; Office of Medical Student Research, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.; Department of Psychiatry and Behavioral Sciences, Oklahoma State University Center for Health Sciences, Tulsa, OK, USA.
Jazyk: angličtina
Zdroj: Diabetic medicine : a journal of the British Diabetic Association [Diabet Med] 2021 Jul 21, pp. e14653. Date of Electronic Publication: 2021 Jul 21.
DOI: 10.1111/dme.14653
Abstrakt: Aims: Currently, there is a growing body of research demonstrating that spin - the misinterpretation and distortion of a study's findings - is common in different fields of medicine. To our knowledge, no study has investigated its presence in systematic reviews focused on diabetic therapies.
Methods: We performed a cross-sectional study by searching MEDLINE and Embase for systematic reviews focused on pharmacologic treatments for type 2 diabetes mellitus. Our search retrieved 26,490 records, from which 199 studies were extracted in a masked, duplicate fashion. Each study was evaluated for the nine most severe types of spin and other study design parameters. Spin was presented as frequencies and odds ratios to identify associations between study characteristics.
Results: Spin was identified in the abstracts of 15 systematic reviews (15/199, 7.5%). Spin type 5 was the most common type identified (7/199, 3.5%). Spin types 1, 2, 4, and 8 were not identified. In the last 5 years (2016-2021), 7 systematic reviews contained spin within their abstract. There was no association between spins presence and any extracted study characteristic .
Conclusions: Our findings show that spin infrequently occurs in abstracts of systematic reviews focused on pharmacologic therapies for type 2 diabetes mellitus. However, any amount of spin can lead to the distortion of a reader's interpretation of the study's findings. Thus, we provide recommendations with rationale to prevent spin in future systematic reviews.
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Databáze: MEDLINE