[Evaluation of the practice of prescribing oral chemotherapy type "Capecitabine" by medical oncologist: A first study from Morocco].

Autor:	Kharmoum S; Université Mohamed V Suissi Rabat , service d'oncologie médicale, centre hospitalier universitaire de Tanger, Maroc. Electronic address: dr.saoussane.kharmoum@gmail.com., Najdi A; Université Abdelmalek-Essadi, faculté de médecine et de pharmacie de Tanger, département d'épidémiologie et recherche clinique, Tetouen, Maroc., Rahhali R; Université Mohamed V Suissi Rabat , service d'oncologie médicale, centre hospitalier universitaire de Tanger, Maroc., Meliani M; Université Abdelmalek Essadi, CHU de Tanger, service d'oncologie médicale, faculté de médecine et de pharmacie de Tanger, Tetouen, Maroc., Boutayeb S; Université Mohamed-V suissi, institut nationale d'oncologie, faculté de médecine et de Pharmacie de Rabat, service d'oncologie médicale, Rabat, Maroc., Mrabti H; Université Mohamed-V suissi, institut nationale d'oncologie, faculté de médecine et de Pharmacie de Rabat, service d'oncologie médicale, Rabat, Maroc., El Ghissassi I; Université Mohamed-V suissi, institut nationale d'oncologie, faculté de médecine et de Pharmacie de Rabat, service d'oncologie médicale, Rabat, Maroc., Afqir S; Université Mohamed-laawal, centre d'oncologie d'Oujda, faculté de médecine et de pharmacie d'oujda, service d'oncologie médicale, Oujda, Maroc., Mellas N; Université Sidi-Mohamed-Ben-Abdellah, CHU d'Hassan-II Fès, faculté de médecine et de pharmacie de FES, service d'oncologie médicale, Fès, Maroc., Ichou M; Université Mohamed-V suissi, hôpital universitaire militaire de Rabat, département d'oncologie médicale, Rabat, Maroc., El M'Rabet FZ; Université Abdelmalek Essadi, CHU de Tanger, service d'oncologie médicale, faculté de médecine et de pharmacie de Tanger, Tetouen, Maroc., Errihani H; Université Mohamed-V suissi, institut nationale d'oncologie, faculté de médecine et de Pharmacie de Rabat, service d'oncologie médicale, Rabat, Maroc.
Jazyk:	francouzština
Zdroj:	Bulletin du cancer [Bull Cancer] 2021 Oct; Vol. 108 (10), pp. 940-947. Date of Electronic Publication: 2021 Jul 17.
DOI:	10.1016/j.bulcan.2021.04.019
Abstrakt:	Introduction: Oral anticancer therapy is becoming increasingly developed; their prescription has become a common practice in oncology. However, there is a variability and diversity in prescription practice. Its magnitude has been very little studied in scientific literature. To our knowledge, this is the first study in Morocco and North Africa to evaluate the practice of prescribing oral chemotherapy. Methods: The authors conducted a national exhaustive cross-sectional survey, to evaluate the practice of the oral chemotherapy "Capecitabine" type prescription by Moroccan oncologists and to identify strategies to promote an adherence to oral anti-neoplasic therapy. Results: Ninety-one medical oncologists answered out of 118, from public oncology centres (29.7%), Hospital University (58.2%), and private sector (12.1%). Thirty-four of the oncologists replied by email, 33 through phone conversation and 24 by filling paper questionnaires. In total, 32% of the cases were handwritten prescriptions, and 51.6% electronically generated. Forty-six percent of medical oncologists dedicated more time to the oral chemotherapy type Capecitabine prescription versus its intravenous equivalent 5FU. However, 33% medical oncologists take less time to this prescription, and 20.9% of them take the same time. Adherence to oral chemotherapy was evaluated by simply questioning of patients in most of the cases (94%) and 4% of medical oncologist declared that they did not evaluate this adherence. In total, 87.9% of Moroccan medical oncologists revealed that they have not received any specific training in the therapeutic education of the patient with oral anti-cancer treatment. Conclusion: In Morocco, there is a great variability in prescription and follow-up practice for patients receiving oral chemotherapy. There is a lack of a national standardization with regards to the procedures of prescribing and monitoring patients to ensure the quality and safety of the oral chemotherapy prescription. (Copyright © 2021 Société Française du Cancer. Published by Elsevier Masson SAS. All rights reserved.)
Databáze:	MEDLINE
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