Fatores associados ao óbito em casos confirmados de COVID-19 no estado do Rio de Janeiro.

Autor: Cini Oliveira M; Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil. cini.marcella@gmail.com., de Araujo Eleuterio T; Instituto de Estudos em Saúde Pública / Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.; Faculdade de Enfermagem, Universidade do Estado do Rio de Janeiro, Rio de Janeiro, Brasil., de Andrade Corrêa AB; Instituto de Física, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil., da Silva LDR; Departamento de Medicina Preventiva, Instituto de Estudos em Saúde Pública / Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil., Rodrigues RC; Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil., de Oliveira BA; Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil., Martins MM; Department of Child Neurology, Martagão Gesteira Institute of Childcare and Pediatrics, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Raymundo CE; Instituto de Estudos em Saúde Pública / Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil., de Andrade Medronho R; Instituto de Estudos em Saúde Pública / Faculdade de Medicina, Universidade Federal do Rio de Janeiro, Rio de Janeiro, Brasil.
Jazyk: angličtina
Zdroj: BMC infectious diseases [BMC Infect Dis] 2021 Jul 16; Vol. 21 (1), pp. 687. Date of Electronic Publication: 2021 Jul 16.
DOI: 10.1186/s12879-021-06384-1
Abstrakt: Background: COVID-19 can occur asymptomatically, as influenza-like illness, or as more severe forms, which characterize severe acute respiratory syndrome (SARS). Its mortality rate is higher in individuals over 80 years of age and in people with comorbidities, so these constitute the risk group for severe forms of the disease. We analyzed the factors associated with death in confirmed cases of COVID-19 in the state of Rio de Janeiro. This cross-sectional study evaluated the association between individual demographic, clinical, and epidemiological variables and the outcome (death) using data from the Unified Health System information systems.
Methods: We used the extreme boosting gradient (XGBoost) model to analyze the data, which uses decision trees weighted by the estimation difficulty. To evaluate the relevance of each independent variable, we used the SHapley Additive exPlanations (SHAP) metric. From the probabilities generated by the XGBoost model, we transformed the data to the logarithm of odds to estimate the odds ratio for each independent variable.
Results: This study showed that older individuals of black race/skin color with heart disease or diabetes who had dyspnea or fever were more likely to die.
Conclusions: The early identification of patients who may progress to a more severe form of the disease can help improve the clinical management of patients with COVID-19 and is thus essential to reduce the lethality of the disease.
(© 2021. The Author(s).)
Databáze: MEDLINE
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