First detection and molecular analysis of SARS-CoV-2 from a naturally infected cat from Argentina.

Autor: Fuentealba NA; Laboratorio de Virología, Facultad de Ciencias Veterinarias (FCV), Universidad Nacional de La Plata (UNLP), 60 & 118, La Plata, Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina., Moré G; Laboratorio de Inmunoparasitología, FCV-UNLP, 60 & 118, La Plata, Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina., Bravi ME; Laboratorio de Virología, Facultad de Ciencias Veterinarias (FCV), Universidad Nacional de La Plata (UNLP), 60 & 118, La Plata, Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina., Unzaga JM; Laboratorio de Inmunoparasitología, FCV-UNLP, 60 & 118, La Plata, Buenos Aires, Argentina., De Felice L; Laboratorio de Inmunoparasitología, FCV-UNLP, 60 & 118, La Plata, Buenos Aires, Argentina., Salina M; Laboratorio de Virología, Facultad de Ciencias Veterinarias (FCV), Universidad Nacional de La Plata (UNLP), 60 & 118, La Plata, Buenos Aires, Argentina., Viegas M; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina; Laboratorio de Virología, Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina., Nabaes Jodar MS; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina; Laboratorio de Virología, Hospital de Niños Ricardo Gutiérrez, Buenos Aires, Argentina., Valinotto LE; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina; Centro de investigaciones en Genodermatosis y Epidermólisis Ampollar (CIDEGEA), Hospital de Niños Dr. Ricardo Gutiérrez / Facultad de Medicina, Universidad de Buenos Aires, Buenos Aires, Argentina., Rivero FD; Instituto Multidisciplinario de Salud, Tecnología y Desarrollo (IMSaTeD), CONICET-UNSE, Santiago del Estero, Argentina., Di Lullo D; Instituto Multidisciplinario de Salud, Tecnología y Desarrollo (IMSaTeD), CONICET-UNSE, Santiago del Estero, Argentina., Pecoraro M; Laboratorio de Virología, Facultad de Ciencias Veterinarias (FCV), Universidad Nacional de La Plata (UNLP), 60 & 118, La Plata, Buenos Aires, Argentina., Panei CJ; Laboratorio de Virología, Facultad de Ciencias Veterinarias (FCV), Universidad Nacional de La Plata (UNLP), 60 & 118, La Plata, Buenos Aires, Argentina; Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina. Electronic address: javierpanei@fcv.unlp.edu.ar.
Jazyk: angličtina
Zdroj: Veterinary microbiology [Vet Microbiol] 2021 Sep; Vol. 260, pp. 109179. Date of Electronic Publication: 2021 Jul 08.
DOI: 10.1016/j.vetmic.2021.109179
Abstrakt: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of coronavirus disease 2019 (COVID-19), has rapidly spread worldwide. Studies of transmission of the virus carried out in animals have suggested that certain animals may be susceptible to infection with SARS-CoV-2. The aim of the present study was to investigate the infection of SARS-CoV-2 in pets (18 cats and 20 dogs) from owners previously confirmed as COVID-19-positive. Oropharyngeal and rectal swabs were taken and analyzed by real-time RT-PCR assays, while blood samples were taken for antibody detection. Of the total pets analyzed, one cat was found reactive to SARS-CoV-2 by real-time RT-PCR of an oropharyngeal and a rectal swab. This cat presented only sneezing as a clinical sign. Serological analysis confirmed the presence of antibodies in the serum sample from this cat, as well as in the serum from another cat non-reactive to real-time RT-PCR. Complete sequence and phylogenetic analysis allowed determining that the SARS-CoV-2 genome belonged to the B.1.499 lineage. This lineage has been reported in different provinces of Argentina, mainly in the Metropolitan Area of Buenos Aires. This study notifies the first detection of the natural infection and molecular analysis of SARS-CoV-2 in a cat from Argentina whose owner where COVID-19-positive. Although there is currently no evidence that cats can spread COVID-19, results suggest that health authorities should test pets with COVID-19-positive owners.
(Copyright © 2021. Published by Elsevier B.V.)
Databáze: MEDLINE
Externí odkaz: