| Autor: |
Shabalina IY; Central Tuberculosis Research Institute, Moscow, Russia., Tikhonov AM; Central Tuberculosis Research Institute, Moscow, Russia., Shishova SV; Central Tuberculosis Research Institute, Moscow, Russia., Semenova LA; Central Tuberculosis Research Institute, Moscow, Russia., Sivokozov IV; Central Tuberculosis Research Institute, Moscow, Russia. |
| Jazyk: |
ruština |
| Zdroj: |
Khirurgiia [Khirurgiia (Mosk)] 2021 (7), pp. 84-89. |
| DOI: |
10.17116/hirurgia202107184 |
| Abstrakt: |
Differential diagnosis of pulmonary infiltrates is difficult due to the absence of specific clinical and radiological manifestations. Differential diagnosis of pulmonary infiltrates usually includes the following «triad»: pneumonia, tuberculosis, lung cancer. Diagnosis of pulmonary tuberculosis is based on microbiological examination of sputum and bronchoscopic respiratory samples - bronchial washing and bronchoalveolar lavage. Efficiency of molecular genetic methods (including express tests) in detecting M. tuberculosis DNA can reach 91-98%. Therefore, treatment may be started without data of microbiological examination. Nevertheless, there are rare cases of false-positive results of PCR in patients with non-tuberculous lung lesions. This aspect often results false diagnosis and delayed verification of true cause of lung lesion. Another adverse effect is associated with anti-tuberculosis therapy. Endoscopic transbronchial lung biopsy and its modern version (transbronchial cryobiopsy) as a minimally invasive diagnostic procedure are performed in such patients. These methods require a sufficiently high experience and qualification of specialist and following such aspects as navigation techniques and balloon bronchial blocking. We present this clinical case as a demonstration of modern possibilities of multimodal navigational bronchoscopic diagnosis with transbronchial cryobiopsy for local pulmonary infiltrate. |
| Databáze: |
MEDLINE |
| Externí odkaz: |
|
