Impedimetric cardiac biomarker determination in serum mediated by epoxy and hydroxyl of reduced graphene oxide on gold array microelectrodes.
Autor: | Taniselass S; Faculty of Electronic Engineering Technology, Universiti Malaysia Perlis, Pauh Putra Campus, 02600, Arau, Perlis, Malaysia.; Institute of Nano Electronic Engineering, Universiti Malaysia Perlis, 01000, Kangar, Perlis, Malaysia., Arshad MKM; Faculty of Electronic Engineering Technology, Universiti Malaysia Perlis, Pauh Putra Campus, 02600, Arau, Perlis, Malaysia. mohd.khairuddin@unimap.edu.my.; Institute of Nano Electronic Engineering, Universiti Malaysia Perlis, 01000, Kangar, Perlis, Malaysia. mohd.khairuddin@unimap.edu.my., Gopinath SCB; Institute of Nano Electronic Engineering, Universiti Malaysia Perlis, 01000, Kangar, Perlis, Malaysia.; Faculty of Chemical Engineering Technology, Universiti Malaysia Perlis, 02600, Arau, Perlis, Malaysia., Fathil MFM; Institute of Nano Electronic Engineering, Universiti Malaysia Perlis, 01000, Kangar, Perlis, Malaysia., Ibau C; Institute of Nano Electronic Engineering, Universiti Malaysia Perlis, 01000, Kangar, Perlis, Malaysia., Anbu P; Department of Biological Engineering, College of Engineering, Inha University, Incheon, 402-751, Republic of Korea. |
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Jazyk: | angličtina |
Zdroj: | Mikrochimica acta [Mikrochim Acta] 2021 Jul 15; Vol. 188 (8), pp. 257. Date of Electronic Publication: 2021 Jul 15. |
DOI: | 10.1007/s00604-021-04922-x |
Abstrakt: | A label-free chemical bonding strategy mediated by reduced graphene oxide (rGO) basal plane functional groups has been developed for cardiac Troponin I (cTnI) detection. Four different chemical strategies on respective electrode sensing surface were precedingly examined using electrochemical impedance spectroscopy. The impedimetric assessment was carried out by sweeping frequency at the range 0.1-500 kHz perturbated at a small amplitude of AC voltage (25 mV). The chemical strategy-4 denoted as S-4 shows a significant analytical performance on cTnI detection in spiked buffer and human serum, whereby the pre-mixture of rGO and (3-Aminopropyl)triethoxysilane (APTES) creates a large number of amine sites (-NH (© 2021. The Author(s), under exclusive licence to Springer-Verlag GmbH Austria, part of Springer Nature.) |
Databáze: | MEDLINE |
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