Treatment of keloids and hypertrophic scars. Position statement of the Brazilian expert group GREMCIQ.

Autor: Oliveira GV; Brazilian Society of Dermatology and Dermatologic Surgery and GREMCIQ, Rio de Janeiro, Brazil.; Mario Penna/Luxemburgo Hospital, Keloids and Scars Ambulatory, Belo Horizonte, Brazil., Metsavaht LD; Brazilian Society of Dermatology and Dermatologic Surgery and GREMCIQ, Rio de Janeiro, Brazil.; Santa Casa de Misericórdia, Rio de Janeiro, Brazil., Kadunc BV; Brazilian Society of Dermatology and Dermatologic Surgery and GREMCIQ, Rio de Janeiro, Brazil.; Surgical and Cosmetic Dermatology, São Paulo, Brazil., Jedwab SKK; Brazilian Society of Dermatology and Dermatologic Surgery and GREMCIQ, Rio de Janeiro, Brazil.; Skinlaser Director, São Paulo, Brazil., Bressan MS; Brazilian Society of Dermatology and Dermatologic Surgery and GREMCIQ, Rio de Janeiro, Brazil.; Maura Bressan Dermatology, Campinas, Brazil., Stolf HO; Brazilian Society of Dermatology and Dermatologic Surgery and GREMCIQ, Rio de Janeiro, Brazil.; UNICAMP, Campinas, Brazil., Castro RG; Brazilian Society of Dermatology and Dermatologic Surgery and GREMCIQ, Rio de Janeiro, Brazil.; Santa Casa de Misericórdia de Belo Horizonte, Belo Horizonte, Brazil., Bezerra SMFMC; Brazilian Society of Dermatology and Dermatologic Surgery and GREMCIQ, Rio de Janeiro, Brazil.; Federal University of Pernambuco, Recife, Brazil., Calil DA; Brazilian Society of Dermatology and Dermatologic Surgery and GREMCIQ, Rio de Janeiro, Brazil.; Brazilian Society of Dermatology, São Paulo Session, São Paulo, Brazil., Addor FAZ; Brazilian Society of Dermatology and Dermatologic Surgery and GREMCIQ, Rio de Janeiro, Brazil.; Albert Einstein Hospital, São Paulo, Brazil., Fraga JCS; Brazilian Society of Dermatology and Dermatologic Surgery and GREMCIQ, Rio de Janeiro, Brazil.; Military Hospital, Belo Horizonte, Brazil., Reis CMS; Brazilian Society of Dermatology and Dermatologic Surgery and GREMCIQ, Rio de Janeiro, Brazil.; Dermatology Residency Program, ESCS-DF, Brasilia, Brazil., Reis-Filho E; Brazilian Society of Dermatology and Dermatologic Surgery and GREMCIQ, Rio de Janeiro, Brazil.; Dermatology Residency Program, ESCS-DF, Brasilia, Brazil., Silva MR; EMBRAPA, UFJF, Juiz de Fora, Brazil., Ramos-E-Silva M; Brazilian Society of Dermatology and Dermatologic Surgery and GREMCIQ, Rio de Janeiro, Brazil.; Dermatology Residency Program, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil., Hexsel DM; Brazilian Society of Dermatology and Dermatologic Surgery and GREMCIQ, Rio de Janeiro, Brazil.; International Society for Dermatologic Surgery (ISDS), Hexsel Dermatology Clinics and Brazilian Center for Studies in Dermatology, Porto Alegre, Brazil.
Jazyk: angličtina
Zdroj: Journal of the European Academy of Dermatology and Venereology : JEADV [J Eur Acad Dermatol Venereol] 2021 Nov; Vol. 35 (11), pp. 2128-2142. Date of Electronic Publication: 2021 Jul 15.
DOI: 10.1111/jdv.17484
Abstrakt: Keloids (K) and hypertrophic scars (HS) are abnormal responses to wound healing that occur as the result of dermal inflammation. Despite the advances on their treatment, many patients still suffer from the negative effects of excessive scarring; its approach is impaired by the lack of objective data on different treatments and the large genetic variability among patients and the difficulties in producing multicentre studies. Their incidence among the Brazilian population is high, as the result of an admixture of Amerindians, Europeans and Africans ancestral roots. With the aim of producing multicentre studies on K and HS, a panel of senior Brazilian dermatologists focused on their treatment was invited to contribute with the K and HS Treatment Brazilian Guidelines. In the first part of this study, different treatment modalities for keloids and HS are fully reviewed by the panel. The second part of the study presents a consensus recommendation of treatment for different types of lesions. More than a literature review, this article aims to show the pitfalls and pearls of each therapeutic option, as well as a therapeutic approach by the Panel of Experts on keloids and Scars on a highly mixed population, providing simple guidelines.
(© 2021 European Academy of Dermatology and Venereology.)
Databáze: MEDLINE
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