Extensive standing genetic variation from a small number of founders enables rapid adaptation in Daphnia.

Autor: Chaturvedi A; Laboratory of Aquatic Ecology, Evolution and Conservation, KU Leuven, Leuven, Belgium. anurag.chaturvedi@unil.ch.; Department of Ecology and Evolution, University of Lausanne, Lausanne, Switzerland. anurag.chaturvedi@unil.ch.; Environmental Genomics Group, School of Biosciences, University of Birmingham, Birmingham, UK. anurag.chaturvedi@unil.ch., Zhou J; Environmental Genomics Group, School of Biosciences, University of Birmingham, Birmingham, UK.; Centre for Computational Biology, University of Birmingham, Birmingham, UK., Raeymaekers JAM; Laboratory of Biodiversity and Evolutionary Genomics, KU Leuven, Leuven, Belgium.; Faculty of Bioscience and Aquaculture, Nord University, Bodø, Norway., Czypionka T; Laboratory of Aquatic Ecology, Evolution and Conservation, KU Leuven, Leuven, Belgium., Orsini L; Environmental Genomics Group, School of Biosciences, University of Birmingham, Birmingham, UK., Jackson CE; O'Neill School of Public and Environmental Affairs, Indiana University, Bloomington, IN, USA., Spanier KI; Laboratory of Aquatic Ecology, Evolution and Conservation, KU Leuven, Leuven, Belgium., Shaw JR; O'Neill School of Public and Environmental Affairs, Indiana University, Bloomington, IN, USA., Colbourne JK; Environmental Genomics Group, School of Biosciences, University of Birmingham, Birmingham, UK., De Meester L; Laboratory of Aquatic Ecology, Evolution and Conservation, KU Leuven, Leuven, Belgium.; Leibniz Institut für Gewässerökologie und Binnenfischerei (IGB), Berlin, Germany.; Institute of Biology, Freie Universität Berlin, Berlin, Germany.
Jazyk: angličtina
Zdroj: Nature communications [Nat Commun] 2021 Jul 14; Vol. 12 (1), pp. 4306. Date of Electronic Publication: 2021 Jul 14.
DOI: 10.1038/s41467-021-24581-z
Abstrakt: We lack a thorough understanding of the origin and maintenance of standing genetic variation that enables rapid evolutionary responses of natural populations. Whole genome sequencing of a resurrected Daphnia population shows that standing genetic variation in over 500 genes follows an evolutionary trajectory that parallels the pronounced and rapid adaptive evolution of multiple traits in response to predator-driven natural selection and its subsequent relaxation. Genetic variation carried by only five founding individuals from the regional genotype pool is shown to suffice at enabling the observed evolution. Our results provide insight on how natural populations can acquire the genomic variation, through colonization by a few regional genotypes, that fuels rapid evolution in response to strong selection pressures. While these evolutionary responses in our study population involved hundreds of genes, we observed no evidence of genetic erosion.
(© 2021. The Author(s).)
Databáze: MEDLINE
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