Wounds in chronic leg oedema.

Autor: Burian EA; Department of Dermato-Venereology, Wound Healing Centre, Bispebjerg Hospital, Copenhagen, Denmark., Karlsmark T; Department of Dermato-Venereology, Wound Healing Centre, Bispebjerg Hospital, Copenhagen, Denmark., Nørregaard S; Department of Dermato-Venereology, Wound Healing Centre, Bispebjerg Hospital, Copenhagen, Denmark., Kirketerp-Møller K; Department of Dermato-Venereology, Wound Healing Centre, Bispebjerg Hospital, Copenhagen, Denmark., Kirsner RS; Dr. Phillip Frost Department of Dermatology and Cutaneous Surgery, University of Miami Miller School of Medicine, Miami, Florida, USA., Franks PJ; Centre for Research and Implementation of Clinical Practice, London, UK., Quéré I; Department of Vascular Medicine, Montpellier University Hospital Centre, University of Montpellier, Montpellier, France., Moffatt CJ; Department of Dermato-Venereology, Wound Healing Centre, Bispebjerg Hospital, Copenhagen, Denmark.; Centre for Research and Implementation of Clinical Practice, London, UK.; Nottingham University Hospitals NHS Trust, Nottingham, UK.
Jazyk: angličtina
Zdroj: International wound journal [Int Wound J] 2022 Feb; Vol. 19 (2), pp. 411-425. Date of Electronic Publication: 2021 Jul 13.
DOI: 10.1111/iwj.13642
Abstrakt: Wounds and chronic oedema are common disorders, but rarely studied together. The objective of this cross-sectional study was to investigate the point-prevalence and risk factors of wounds on the leg, in chronic leg oedema. Forty sites in nine countries were included. Of 7077 patients with chronic leg oedema, 12.70% had wounds. Independent risk factors were: peripheral arterial disease (odds ratio (OR) 4.87, 95% confidence intervals (CI) 3.63-6.52), cellulitis within the past 12 months (OR 2.69, 95% CI 2.25-3.21), secondary lymphoedema (OR 2.64, 95% CI 1.93-3.60), being male (OR 2.08, 95% CI 1.78-2.44), being over 85 years of age (OR 1.80, 95% CI 1.23-2.62), underweight (OR 1.79, 95% CI 1.14-2.79), bed bound (OR 1.79, 95% CI 1.01-3.16), chair bound (OR 1.52, 95% CI 1.18-1.97), diabetes (OR 1.47, 95% CI 1.23-1.77), and walking with aid (OR 1·41, 95% CI 1.17-1.69). 43.22% of those with wounds had clinically defined well-controlled oedema, associated with a significantly lower risk of wounds (OR 0.50, 95% CI 0.42-0.58, P < .001). Hard/fibrotic tissue (OR 1.71, 95% CI 1.19-2.48), and a positive Stemmers sign (OR 1.57, 95% CI 1.05-2.35) were associated with wounds. The study reinforces the importance of measures to control oedema, as controlled swelling was associated with a 50% lower risk of wounds.
(© 2021 The Authors. International Wound Journal published by Medicalhelplines.com Inc (3M) and John Wiley & Sons Ltd.)
Databáze: MEDLINE
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