A patient with multiple brown tumors due to secondary hyperparathyroidism: A case report.

Autor:	Messina L; Department of Radiology, University of Rome 'Campus Bio-medico', Via Alvaro del Portillo, 21- 00128 Rome, Italy., Garipoli A; Department of Radiology, University of Rome 'Campus Bio-medico', Via Alvaro del Portillo, 21- 00128 Rome, Italy., Giordano FM; Department of Radiology, University of Rome 'Campus Bio-medico', Via Alvaro del Portillo, 21- 00128 Rome, Italy., Ferrari U; Department of Radiology, University of Rome 'Campus Bio-medico', Via Alvaro del Portillo, 21- 00128 Rome, Italy., Grippo R; Department of Radiology, University of Rome 'Campus Bio-medico', Via Alvaro del Portillo, 21- 00128 Rome, Italy., Sarli M; Department of Radiology, University of Rome 'Campus Bio-medico', Via Alvaro del Portillo, 21- 00128 Rome, Italy., Beomonte Zobel B; Department of Radiology, University of Rome 'Campus Bio-medico', Via Alvaro del Portillo, 21- 00128 Rome, Italy.
Jazyk:	angličtina
Zdroj:	Radiology case reports [Radiol Case Rep] 2021 Jul 02; Vol. 16 (9), pp. 2482-2486. Date of Electronic Publication: 2021 Jul 02 (Print Publication: 2021).
DOI:	10.1016/j.radcr.2021.06.015
Abstrakt:	Brown tumor is an uncommon non-neoplastic radiolucent bone lesion due to a rapid bone loss replaced by haemorrhage and reparative granulation tissue. It is a manifestation of hyperparathyroidism related to the high level of parathyroid hormone and represents a problem linked to the adherence to therapy. We present a case of a 44 years-old Caucasian female with hemodialysis-dependent chronic kidney disease in poor sanitary condition with CT evidence of innumerable and widespread bone tumors. At first, we considered these bone lesions strongly suspicious for metastasis, so we recommended an oncological consultation and laboratory studies, that showed a secondary hyperparathyroidism with elevated serum parathormone level of 923 pg/mL (normal range: 10-70 pg/mL). According to our experience, in case of radiological evidence of multiple bone lesions, a correct medical history is mandatory. When the patient has a history of chronic kidney disease and dialysis and high blood levels of parathyroid hormone are present, secondary hyperparathyroidism should always be considered in the differential diagnosis. (© 2021 The Authors. Published by Elsevier Inc. on behalf of University of Washington.)
Databáze:	MEDLINE
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